Clinical trial · Observational
Patient Journey With Advanced Lung Cancer Positive for ALK Fusion in Brazil
NCT04947683CI-TRIAL-00068457ALKcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Observational, retrospective cohort study that will include patients diagnosed with NSCLC and ALK rearrangement between January 2015 and December 2020.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Carcinoma, Non-Small-Cell Lung | Lung Non-Small Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- - Describe the treatment sequencing of ALK positive advanced NSCLC in a real-world setting.
- timeFrame
- December of 2020
- measure
- - Describe the timelines from the appearance of symptoms, histopathological diagnosis, application of the molecular test, and start of treatment.
- timeFrame
- December of 2020
Secondary outcomes (1)
- measure
- - Estimate the progression-free survival of first-line treatment, and other subsequent lines;
- timeFrame
- December of 2020
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients older than 18 years; * Newly diagnosed advanced stage IIIB-IV NSCLC (AJCC 8th edition) or locally advance/distant relapse in the period of January 2015 to December 2020. * NSCLC with pathological confirmation of ALK rearrangement by immunohistochemistry, fluorescent in situ hybridization (FISH) or next generation sequencing (NGS); * ECOG 0-4; * Patients with CNS metastases are also considered eligible, regardless of the initial treatment instituted. Exclusion Criteria: \- Incomplete medical chart in terms of date of diagnosis, ALK test results and outcomes
References
Publications (0)
Data not yet available
No reference posted for this study.