Clinical trial · Observational
LPN in Patients With High-complex Renal Tumors
Comparison of Laparoscopic Partial Nephrectomy Versus Laparoscopic Radical Nephrectomy in Patients With High-Complexity Renal Tumors: A Propensity Score Matched Analysis
NCT04933604CI-TRIAL-00052394completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study aims to investigate the rationale for LPN in patients with high-complexity renal tumors in terms of oncologic and functional outcomes.
Conditions
Conditions (10)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Kidney Injury | — | UNRESOLVED | — |
| Kidney Ischemia | — | UNRESOLVED | — |
| Kidney Neoplasms | Kidney Neoplasm | ONTOLOGY_EXACT | 0.90 |
| Oncology | — | UNRESOLVED | — |
| Renal Cancer | — | UNRESOLVED | — |
| Renal Cell Carcinoma | Renal Cell Carcinoma | CURATED_BROADER | 0.80 |
| Renal Neoplasm | Kidney Neoplasm | ALIAS | 0.90 |
| Surgery | — | UNRESOLVED | — |
| Urologic Cancer | — | UNRESOLVED | — |
| Urologic Neoplasms | Urinary Tract Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| laparoscopic partial nephrectomy | Procedure | — | UNRESOLVED |
| Laparoscopic radical nephrectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- LPN group
- description
- 39 patients with high complexity renal tumors who underwent laparoscopic partial nephrectomy
- interventionNames
- Procedure: laparoscopic partial nephrectomy
- label
- LRN group
- description
- 39 patients with high complexity renal tumors who underwent laparoscopic radical nephrectomy
- interventionNames
- Procedure: Laparoscopic radical nephrectomy
Primary outcomes (8)
- measure
- Operation time
- timeFrame
- at the end of the surgery
- description
- time from onset to complete of surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with complete data * Patients with single renal tumor on the effected side * Patients who approved the written consent form Exclusion Criteria: * Patients who not approved the written consent form * Patients with incomplete data * Patients with low or mild complexity renal tumors
References
Publications (3)
- RESULTKim SP, Campbell SC, Gill I, Lane BR, Van Poppel H, Smaldone MC, Volpe A, Kutikov A. Collaborative Review of Risk Benefit Trade-offs Between Partial and Radical Nephrectomy in the Management of Anatomically Complex Renal Masses. Eur Urol. 2017 Jul;72(1):64-75. doi: 10.1016/j.eururo.2016.11.038. Epub 2016 Dec 14. PMID 27988238
- RESULTMir MC, Derweesh I, Porpiglia F, Zargar H, Mottrie A, Autorino R. Partial Nephrectomy Versus Radical Nephrectomy for Clinical T1b and T2 Renal Tumors: A Systematic Review and Meta-analysis of Comparative Studies. Eur Urol. 2017 Apr;71(4):606-617. doi: 10.1016/j.eururo.2016.08.060. Epub 2016 Sep 7. PMID 27614693
- RESULTYang F, Zhou Q, Xing N. Comparison of survival and renal function between partial and radical laparoscopic nephrectomy for T1b renal cell carcinoma. J Cancer Res Clin Oncol. 2020 Jan;146(1):261-272. doi: 10.1007/s00432-019-03058-z. Epub 2019 Nov 1. PMID 31677114