Clinical trial · Interventional
Outcomes After Dorsal Wrist Ganglia Excision With or Without PIN
Outcomes of Surgical Excision of Dorsal Wrist Ganglia With or Without Partial Wrist Denervation
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Study recruitment stopped due to recruitment problems
Summary
Brief summary (as posted)
The purpose of this study is to determine if a statistical significance exists between outcomes of patients treated for dorsal wrist ganglion cyst with excision alone versus excision and the addition of a partial wrist denervation by resecting the common terminal sensory branch of the PIN (posterior interosseus nerve). Our hypothesis is that addition of PIN improves outcome after dorsal wrist ganglion excision as indicated by post-operative pain, function, ability to perform activities of daily living, and physical exam findings.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Denervation Atrophy | — | UNRESOLVED | — |
| Ganglion Cysts | — | UNRESOLVED | — |
| Hand Ganglion | — | UNRESOLVED | — |
| Wrist Ganglion | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Dorsal wrist ganglion alone (DWG) | Procedure | — | UNRESOLVED |
| DWG/PIN | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Dorsal wrist ganglion alone (DWG)
- description
- Dorsal wrist ganglion excision alone
- interventionNames
- Procedure: Dorsal wrist ganglion alone (DWG)
- type
- ACTIVE_COMPARATOR
- label
- DWG with PIN
- description
- Dorsal wrist ganglion excision with posterior interosseus neurectomy (PIN)
- interventionNames
- Procedure: DWG/PIN
Primary outcomes (4)
- measure
- Pain measured with the Visual Analog Pain Scale (VAS)
- timeFrame
- Preop to One Year Post-Op
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Greater than or equal to 18 years of age * Gender: male/female (non-pregnant) * Diagnosis of symptomatic (pain and limited ability to perform activities of daily living) dorsal wrist ganglion cyst * Subjects who have chosen surgical management for their ganglion cyst diagnosis * Fluent in written and spoken English * Subject is able to provide voluntary, written informed consent * Subject, in the opinion of the clinical investigator, is able to understand the clinical investigation and is willing to perform all study procedures and follow-up visits * Non-Prisoners Exclusion Criteria: * Less than 18 years of age * Non-elective surgery for this diagnosis * Chronic wrist instability of the operative extremity * Comorbid neurologic maladies of the operative extremity * Prior wrist surgery on either extremity * Non-English speaking * Prisoners * Pregnancy * Cognitive Impairment
References
Publications (18)
- BACKGROUNDHo PC, Griffiths J, Lo WN, Yen CH, Hung LK. Current treatment of ganglion of the wrist. Hand Surg. 2001 Jul;6(1):49-58. doi: 10.1142/s0218810401000540. PMID 11677666
- BACKGROUNDThornburg LE. Ganglions of the hand and wrist. J Am Acad Orthop Surg. 1999 Jul-Aug;7(4):231-8. doi: 10.5435/00124635-199907000-00003. PMID 10434077
- BACKGROUNDAngelides AC, Wallace PF. The dorsal ganglion of the wrist: its pathogenesis, gross and microscopic anatomy, and surgical treatment. J Hand Surg Am. 1976 Nov;1(3):228-35. doi: 10.1016/s0363-5023(76)80042-1. PMID 1018091
- BACKGROUNDClay NR, Clement DA. The treatment of dorsal wrist ganglia by radical excision. J Hand Surg Br. 1988 May;13(2):187-91. doi: 10.1016/0266-7681_88_90135-0. PMID 3385297
- BACKGROUNDDellon AL, Seif SS. Anatomic dissections relating the posterior interosseous nerve to the carpus, and the etiology of dorsal wrist ganglion pain. J Hand Surg Am. 1978 Jul;3(4):326-32. doi: 10.1016/s0363-5023(78)80032-x. PMID 681715
- BACKGROUNDCarr D, Davis P. Distal posterior interosseous nerve syndrome. J Hand Surg Am. 1985 Nov;10(6 Pt 1):873-8. doi: 10.1016/s0363-5023(85)80165-9. PMID 4078272
- BACKGROUNDDellon AL. Partial dorsal wrist denervation: resection of the distal posterior interosseous nerve. J Hand Surg Am. 1985 Jul;10(4):527-33. doi: 10.1016/s0363-5023(85)80077-0. PMID 4020064
- BACKGROUNDFaithfull DK, Seeto BG. The simple wrist ganglion--more than a minor surgical procedure? Hand Surg. 2000 Dec;5(2):139-43. doi: 10.1142/s0218810400000235. PMID 11301508