Clinical trial · Observational
Longitudinal Investigation of Cancer-related Fatigue and Its Treatment (LIFT Project)
NCT04921644CI-TRIAL-00087698active not recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The LIFT project aims to thoroughly investigate the current status of health care in Germany regarding cancer-related fatigue from the institutional, professionals' and patients' perspective.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer-related Fatigue | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- patient cohort
- description
- Newly diagnosed patients with colon, rectum, liver, pancreas or lung cancer, malignant melanoma, breast or other gynecological cancers, prostate, kidney, bladder or thyroid gland cancer, non-Hodgkin lymphoma or leukemia recruited approximately 6 months after diagnosis and followed up to 2 years post-diagnosis. No intervention.
Primary outcomes (4)
- measure
- Fatigue severity
- timeFrame
- 6 months after diagnosis to 2 years post-diagnosis
- description
- assessed by EORTC QLQ-FA12 (European Organisation for Research and Treatment of Cancer Quality of Life Fatigue Questionnaire). The items are rated on a 4-point Likert scale ranging from 1 (not at all) to 4 (very much) with higher scores meaning a higher level of fatigue.
- measure
- Impact of fatigue
- timeFrame
- 6 months after diagnosis to 2 years post-diagnosis
- description
- assessed by the Brief Fatigue Inventory (BFI). The BFI consists of an 11-point numerical rating scale ranging from 0 (no fatigue) to 10 (as bad as you can imagine) with higher scores signifying higher intensity and impairment.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * ≥ 18 years of age * Newly diagnosed with a primary tumor of one of the following malignant neoplasms: colon (C18), rectum (C19-20), liver (C22), pancreas (C25), lung (C33-34), malignant melanoma (C43), breast (C50, only female), cervix (C53), endometrium (C54.1), ovaries (C56), prostate (C61), kidney (C64), bladder (C67), thyroid gland (C73), non-Hodgkin lymphoma (C82-88), leukemia (C91-C95) * Having received or receiving at enrolment at least one of the following treatments: chemotherapy, radiotherapy, hormone therapy, targeted or immune therapy * Able to understand and follow the study protocol Exclusion Criteria: * Carcinoma in situ * Any additional malignant or unclear neoplasm before or since time of diagnosis of the considered primary tumor, except unspecified neoplasm of skin (C44)
References
Publications (4)
- DERIVEDWagner AS, Milzer M, Schmidt ME, Kiermeier S, Maatouk I, Steindorf K. Nurses' Knowledge of Cancer-Related Fatigue and the Coverage of This Subject in Nursing Training: A Cross-Sectional Study. J Nurs Res. 2025 Apr 1;33(2):e379. doi: 10.1097/jnr.0000000000000666. PMID 40162696
- DERIVEDWagner AS, Wehlen L, Milzer M, Schmidt ME, Kiermeier S, Maatouk I, Steindorf K. Physicians' perspectives on cancer-related fatigue management and their suggestions for improvements in medical training: a cross-sectional survey study in Germany. Support Care Cancer. 2024 Nov 14;32(12):788. doi: 10.1007/s00520-024-08978-2. PMID 39537876
- DERIVEDMilzer M, Wagner AS, Schmidt ME, Maatouk I, Hermann S; Cancer Registry of Baden-Wurttemberg; Kiermeier S, Steindorf K. Patient-physician communication about cancer-related fatigue: a survey of patient-perceived barriers. J Cancer Res Clin Oncol. 2024 Jan 25;150(2):29. doi: 10.1007/s00432-023-05555-8. PMID 38270814
- DERIVEDMilzer M, Wagner AS, Steindorf K, Kiermeier S, Schmidt ME, Maatouk I. Psycho-oncologists' knowledge of cancer-related fatigue and the targets for improving education and training: results from a cross-sectional survey study. Support Care Cancer. 2023 Jun 23;31(7):412. doi: 10.1007/s00520-023-07882-5. PMID 37351639