Clinical trial · Interventional
Dexmedetomidine in Erector Spinae Block in Postoperative Analgesia
Can Dexmedetomidine Improve the Analgesic Duration and Efficacy of Erector Spinae Plane Block in Breast Cancer Surgeries?
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
60 female patients scheduled for breast cancer surgeries, allocated in 3 groups for erector spinae block with bupivacaine and erector spinae block with dexmedetomidine added to bupivacaine and control group. During anesthesia: total intraoperative fentanyl required will be recorded. After surgery the first time of request for analgesic will be recorded. after request of analgesia all patients will be connected to PCA device containing morphine solution, the amount of morphine consumed during the first 24 hours will be recorded.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Postoperative Pain | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| erector spinae block with bupivacaine | Procedure | — | UNRESOLVED |
| erector spinae block with bupivacaine + dexmedetomidine | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- erector spinae block
- description
- erector spinae block with 20 ml bupivacaine
- interventionNames
- Procedure: erector spinae block with bupivacaine
- type
- EXPERIMENTAL
- label
- erector spinae block + dexmedetomidine
- description
- erector spinae block with 19 ml bupivacaine + dexmedetomidine
- interventionNames
- Procedure: erector spinae block with bupivacaine + dexmedetomidine
- type
- NO_INTERVENTION
- label
- control group
- description
- standard general anesthesia without any block
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Provision of signed and dated informed consent form * Stated willingness to comply with all study procedures and availability for the duration of the study * Female, aged (18-70) years * Belongs to American Society of Anaesthesiologists physical status class II. * Scheduled for breast cancer surgeries. Exclusion Criteria: * Patient refusal. * Local infection at the site of the block. * Cardiac dysfunction (ejection fraction \<45%). * Preexisting neurological or psychiatric disease, communication difficulties, inability to use the patient-controlled analgesia (PCA) device. * Allergy to one of the study drugs. * Pregnancy. * Coagulopathy (PC \<60% and platelet count\<100.000).
References
Publications (0)
Data not yet available