Clinical trial · Interventional
Minimally Invasive Evaluation of Dyspepsia by Combined Magnetically Controlled Capsule Endoscopy and Urea Breath Test: a Pilot Prospective Cohort Study
NCT04918472CI-TRIAL-00068970MCUDYSPEPSIAcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The combined diagnostic accuracy of MCCE and UBT in Hong Kong patients with uninvestigated dyspepsia between age 35 to 60 years for structural pathology and HP infection is comparable to that of conventional UGI endoscopy with histological examination for HP
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Dyspepsia | — | UNRESOLVED | — |
| Gastroesophageal Reflux | — | UNRESOLVED | — |
| Pancreatobiliary Disease | — | UNRESOLVED | — |
| Peptic Ulcer Disease | — | UNRESOLVED | — |
| Ugi Malignancies | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MCCE | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- MCCE
- description
- Magnetically controlled capsule endoscopy will be performed before UGI endoscopy.
- interventionNames
- Procedure: MCCE
Primary outcomes (1)
- measure
- The combined diagnostic accuracy of MCCE and UBT as gold standard
- timeFrame
- 2 weeks
- description
- The combined diagnostic accuracy of MCCE and UBT in Hong Kong patients with uninvestigated dyspepsia between age 35 to 60 years for structural pathology and HP infection using conventional UGI endoscopy and histological examination for HP as gold standard
Secondary outcomes (3)
- measure
- The sensitivity and specificity of MCCE for clinically significant structural pathology in UGI (defined as peptic ulcers, cancers, reflux esophagitis) as gold standard
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 35 Years
- Maximum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: * Age 35 to 60 * Patients with uninvestigated dyspeptic symptoms including epigastric pain or burning, bloating, postprandial fullness, belching, early satiety and nausea * Patients who are able to provide written informed consent to participate in the study and comply with the study procedures. Exclusion Criteria: * Unable to provide written informed consent * Patients with contraindications for conventional UGI endoscopy or MCCE due to comorbidities * Patients with dysphagia, gastroparesis, gastrointestinal (GI) tract obstruction, or surgically altered anatomy of the GI tract * Patients with a permanent pacemaker, or implantable cardioverter-defibrillator * Patients with any electronic/magnetic/mechanically controlled devices e.g. sacral nerve stimulators, bladder stimulators * Patients with known inflammatory bowel disease, cancer of the GI tract * Patients who are pregnant or lactating
References
Publications (0)
Data not yet available
No reference posted for this study.