Clinical trial · Interventional
Effect of Vitamin D Oral Supplementation in Poly Csytic Ovarian Women Resistant to Clomiphene Citrate
Effect of Vitamin D Oral Supplementation in Poly Cystic Ovarian Women Resistant to Clomiphene Citrate
NCT04916925CI-TRIAL-00052140unknownPhase 1 / Phase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
effect of vitamin D oral supplementation in poly csytic ovarian women resistant to clomiphene citrate
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Clomiphene Allergy | — | UNRESOLVED | — |
| Polycystic Ovary Syndrome | — | UNRESOLVED | — |
| Vitamin D Deficiency | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Clomid | Drug | — | UNRESOLVED |
| Vitamin D | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- pcos resistant to cc plus vit d
- description
- 100 patients who are PCOS and resist CC will receive Vitamin D 10000 IU orally plus 150mg clomid orally for 3 months number and size of growing follicles will be monitored
- interventionNames
- Drug: Vitamin D
- Drug: Clomid
Primary outcomes (1)
- measure
- number of the ovulated follicles
- timeFrame
- 36 hours of taking HCG injection
- description
- Number of ovulated follicles by trans vaginal ultra sound signs of ovulation
Secondary outcomes (2)
- measure
- pregancy rate
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria: * Age: 18-40 years 2- Polycystic ovarian syndrome diagnosis made according to ESHRE/ASRM criteria. 1. Polycystic ovaries (either 12 or more follicles or increased ovarian volume \[\> 10 cm3 2. Oligo-ovulation or anovulation 3. Clinical and/or biochemical signs of hyperandrogenism (Azziz, 2006). 3- PCOS infertile women resistant to CC for 3 cycles. clomiphene citrate resistance means failure to ovulate with 3 months use of clomid at 150 mg/day for 5 days Exclusion Criteria: * Causes of infertility other than PCOS. 1. Male factor.(normal semen analysis) 2. Other factors e.g. endometriosis 3. Tubal factor. (normal hysterosalpingography) 4. Premature ovarian failure: Day 3 FSH \> 14 mlu/ml or antimullerian hormone \<1 ng/ml. 5. Normal ultrasound except for criteria of PCO * Causes of anovulation other than PCOS. * Patients with hyperprolactinemia * Patients with thyroid dysfunction. * Current or in last six months use of vit D treatment.
References
Publications (0)
Data not yet available
No reference posted for this study.