Clinical trial · Observational
Circulating Fetal Cells and Breast Cancer
Fetal Microchimerism and Fetal Stem Cells in Breast Cancer: Analysis of Circulating Fetal Cell Sub-populations in Women With Breast Cancer. CIRCULATING FETAL CELLS AND BREAST CANCER
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
After pregnancy, fetal cells remain in a woman's body for years. These cells may be involved in different physiological situations (e.g. wound healing) and diseases (e.g. cancer).The study will evaluate the level of circulating fetal immune cells in patients with breast cancer vs controls with benign breast tumors, and further characterize these fetal cells. Patients participation will be limited to accepting that an additional blood sample is collected on the day of their preop consultation and blood test.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood sample | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Patients
- description
- women 18-50 years * with previous history of a male birth * scheduled for malignant breast tumor surgery
- interventionNames
- Other: Blood sample
- label
- Controls
- description
- women 18-50 years * with previous history of a male birth * scheduled for benign breast tumor surgery * or cancer free
- interventionNames
- Other: Blood sample
Primary outcomes (1)
- measure
- Percentages of fetal cells in each immune cell subpopulation.
- timeFrame
- 3 years
- description
- Using fluorescence activated cell sorting method.
Secondary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria: * women aged 18-50 * having had a male child * informed and not having objected to participating in the research. Patients: \- having a diagnosis of breast cancer Controls: * operated on for benign breast tumors * cancer free Exclusion Criteria: * autoimmune disease * immunomodulatory treatment * history of cancer other than breast cancer * ongoing hormonal treatment * women not affiliated to the social security * under AME (state medical aid) * under tutorship / curatorship
References
Publications (0)
Data not yet available