Clinical trial · Observational
A-EYE: A Mixed Quantitative and Qualitative Study to Develop and Evaluate the Application of Artificial Intelligence (AI) Methods Using Retinal Imaging for the Identification of Adverse Retinal Changes Associated With Cancer Therapies.
NCT04901468CI-TRIAL-00062094A-EYEunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a data collection study involving the gathering of clinical data and OCT (optical coherence tomography) scans from 350 patients. The purpose of this study is to gather data to help develop an AI algorithm to detect eye abnormalities specifically those related to certain cancer treatments. At the end of the study interviews will be held with expert ophthalmologists to assess the acceptability of implementing AI into clinical practice.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| All Comers | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| No Intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Measure of the diagnostic accuracy of the AI algorithm against gold standard clinical assessment associated with cancer treatment.
- timeFrame
- 12 months
Secondary outcomes (1)
- measure
- Sensitivity of the AI in identifying clinically relevant lesions as defined by an ophthalmologist. Specificity of the AI in identifying clinically relevant lesions as defined by an ophthalmologist.
- timeFrame
- 12 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Patients are eligible for the study if all inclusion criteria are met: 1. Voluntary informed consent. 2. Aged at least 18 years. 3. Fully registered patient attending the Manchester Royal Eye Hospital 4. Patients are having an optical diagnostic imaging as part of their standard of care. Exclusion Criteria: Patients are excluded from the study if any of the following criteria apply: 1\. Patient who are deemed clinically unable to be scanned by healthcare professional.
References
Publications (0)
Data not yet available
No reference posted for this study.