Clinical trial · Interventional
Efficacy and Safety of Obturator Nerve Block During Transurethral Resection on Non-muscle Invasive Intermediate and High Risk Lateral Wall Bladder Tumours
Efficacy and Safety of Obturator Nerve Block During Transurethral Resection on Non-muscle Invasive Intermediate and High Risk Lateral Wall Bladder Tumours Comparing Nerve Stimulator-guided Obturator Nerve Block With Spinal Anaesthesia and Spinal Anaesthesia: A Prospective Randomized Controlled Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In this prospective randomized controlled study, the effects of obturator nerve block (ONB) on obturator reflex, incomplete resection, perforation, tumor recurrence and progression, presence of muscle tissue in the specimen, need for second transurethral resection of bladder tumours (TURBT) and postoperative complications were investigated in patients who underwent TURBT for intermediate and high risk lateral wall non-muscle invasive bladder tumours (NMIBC).
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bladder Cancer Stage 0 | Malignant Bladder Neoplasm | CURATED_BROADER | 0.78 |
| Bladder Cancer Stage I | Malignant Bladder Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Nerve Stimulator-guided Obturator Nerve Block | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Obturator Nerve Block + Spinal Anaesthesia
- description
- Patients who underwent obturator nerve block with spinal anesthesia prior to TURBT
- interventionNames
- Procedure: Nerve Stimulator-guided Obturator Nerve Block
- type
- SHAM_COMPARATOR
- label
- Spinal Anaesthesia
- description
- Patients who underwent spinal anesthesia prior to TURBT
- interventionNames
- Procedure: Nerve Stimulator-guided Obturator Nerve Block
Primary outcomes (1)
- measure
- Rate of Obturator Reflex
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * Lateral wall intermediate and high risk non-muscle invasive bladder cancer Exclusion Criteria: * Low risk non-muscle invasive bladder cancer * Contraindications for spinal anesthesia * History of allergy to local anesthetic agents * Coagulopathy * Neuromuscular diseases affecting the central nervous system * Obturator nerve injury
References
Publications (0)
Data not yet available