Clinical trial · Observational
A Non Interventional Pilot Study on Machine Learning for ILD Detection Based on the Patient Data From Digital Devices in Unresectable Stage III Non-Small Cell Lung Cancer Patients Receiving Durvalumab
NCT04884269CI-TRIAL-00074048iDETECTcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Objective in this study is to investigate feasibility of developing machine-learning based model for the identification of future development of diagnosed Grade 2 and higher ILD and of disease progression in patients with unresectable Stage III NSCLC receiving durvalumab
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Carcinoma, Non-Small-Cell Lung | Lung Non-Small Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Grade 2 and higher ILD including radiation pneumonitis
- timeFrame
- 6 months
Secondary outcomes (1)
- measure
- Disease progression
- timeFrame
- 6 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: * Patient who provided written signed informed consent prior to the first study-specific procedures. * Patient who receives durvalumab for unresectable stage III NSCLC at first time following chemoradiation therapy * Patient whose performance status showed 0 or 1 prior to durvalumab treatment * Patient who is able and willing to wear the devices daily for up to 6 months as instructed Exclusion Criteria: * Patient under immunotherapy treatment other than durvalumab. * Patient had received prior immunotherapy * Patient under the interventional clinical studies using unapproved drugs or off-label use of drugs * Patient who showed ILD (including radiation pneumonitis) of Grade 2 and higher, after consolidated chemoradiation therapy. * Patient who is judged as not suitable for the study by the study site investigators, in terms of fitting wearable devices, presence of silicone or metallic allergy
References
Publications (0)
Data not yet available
No reference posted for this study.