Clinical trial · Observational
PRedictiOn Algorithms for the DeTECTion of Early Stage Pancreatic Cancer
NCT04883450CI-TRIAL-00073002PRO-TECTunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Conduct a prospective study to assess the accuracy of a pancreatic cancer risk prediction model.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
| Pancreatic Ductal Adenocarcinoma (PDAC) | Pancreatic Ductal Adenocarcinoma | ONTOLOGY_EXACT | 0.85 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Magnetic resonance imaging (MRI) | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Risk of pancreatic cancer
- description
- Subjects with an increased predicted 18-month risk of pancreatic cancer
- interventionNames
- Diagnostic Test: Magnetic resonance imaging (MRI)
Primary outcomes (1)
- measure
- Incidence of pancreatic ductal adenocarcinoma (PDAC) in the high predicted risk group
- timeFrame
- 18-Month
- description
- Enrolled subjects will be followed for 18 months to determine the incidence rate of PDAC
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 50 Years
- Maximum age
- 84 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patient must have 6 months of membership 2. Patient has a measure for weight, Hemoglobin A1C, and Alanine transaminase (ALT) within the past 6 months 3. Patient must have an increased predicted 18-month risk of pancreatic cancer based on the PRO-TECT model 4. Speaks English or Spanish Exclusion Criteria: 1. Previous or current history of pancreatic cancer 2. Metastatic cancer 3. Current active cancer or undergoing chemotherapy for cancer 4. Currently pregnant or breastfeeding 5. Class IV heart failure 6. Cirrhosis with ascites and/or varices 7. Currently in a skilled nursing facility or under hospice care 8. Has metal parts or implanted devices in the body, such as a pacemaker, defibrillator, or shrapnel 9. End stage renal disease 10. Cognitive impairment such that the person is unable to provide informed consent
References
Publications (0)
Data not yet available
No reference posted for this study.