Clinical trial · Interventional
Vegetable Intake Effect on Heterocyclic Amine Metabolism
Effect of Vegetable Intake on Heterocyclic Amine Metabolism in Humans
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): PI left the university
Summary
Brief summary (as posted)
This is a randomized trial with crossover design, where each participant will undergo four study phases with a different test meal at the end of each phase. Every phase will consist of subjects consuming for six days their normal diet excluding cruciferous and apiaceous vegetables, alcohol, and caffeine. The participants will refrain from meat products for 24 hours prior to the test meal. On day seven of each phase and after an overnight fast, subjects will be randomly assigned to eat one of four meals: 1. grilled hamburger with no vegetables 2. grilled hamburger with steamed broccoli and Brussels sprouts 3. grilled hamburger with steamed parsnips, fresh parsley, and celery sticks 4. grilled hamburger with steamed broccoli, Brussels sprouts, and parsnips plus fresh parsley and celery sticks.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| grilled hamburger (7 oz) with no vegetables | Other | — | UNRESOLVED |
| grilled hamburger (7 oz) with steamed broccoli and Brussels sprouts (3g/kg body weight combined) | Other | — | UNRESOLVED |
| grilled hamburger (7 oz) with steamed broccoli, Brussels sprouts, and parsnips plus fresh parsley and celery sticks (6g/kg body weight combined). | Other | — | UNRESOLVED |
| grilled hamburger (7 oz) with steamed parsnips, fresh parsley, and celery sticks (3g/kg body weight combined) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- Test meal 1 - grilled hamburger (7 oz) with no vegetables
- description
- Randomly assigned participants are given grilled hamburger (7 oz) with no vegetables
- interventionNames
- Other: grilled hamburger (7 oz) with no vegetables
- type
- EXPERIMENTAL
- label
- Test meal 2 - grilled hamburger with steamed broccoli and Brussels sprouts
- description
- Randomly assigned participants are given grilled hamburger with steamed broccoli and Brussels sprouts (3g/kg body weight combined)
- interventionNames
- Other: grilled hamburger (7 oz) with steamed broccoli and Brussels sprouts (3g/kg body weight combined)
- type
- EXPERIMENTAL
- label
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * 18 years old or older * Healthy * Non-smoker Exclusion Criteria: * No history of gastrointestinal, hepatic, or renal disorders * Not currently taking any prescription or over-the-counter medications * Not currently taking any herbal/vitamins supplements * Not pregnant or lactating * No allergies or intolerances to the foods that will be used in the study (parsnips, parsley, celery, broccoli, Brussels sprouts, and hamburger)
References
Publications (0)
Data not yet available