Clinical trial · Interventional
Mind-body Resiliency Intervention for Fear of Cancer Recurrence
IN FOCUS: A Multimodal Mind-Body Intervention for Fear of Recurrence Among Cancer Survivors
NCT04876599CI-TRIAL-00070439completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to test the feasibility of a virtual, group mind-body resiliency intervention adapted to target fear of recurrence (FOR) among cancer survivors.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Coping Behavior | — | UNRESOLVED | — |
| Coping Skills | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| IN FOCUS | Behavioral | — | UNRESOLVED |
| Usual Care | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Intervention (IN FOCUS)
- description
- Participants will be randomly assigned and participate in eight weekly virtual group sessions to learn mind-body, cognitive behavioral, and positive psychology skills.
- interventionNames
- Behavioral: IN FOCUS
- type
- ACTIVE_COMPARATOR
- label
- Usual Care
- description
- Participants will be randomly assigned and receive usual care, which is a referral for virtual group supportive services for cancer survivors provided in the community.
- interventionNames
- Behavioral: Usual Care
Primary outcomes (2)
- measure
- Feasibility: Retention Rate
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * History of non-metastatic, localized, or regional solid or blood malignancy(ies) * Completion of primary cancer treatment (i.e., radiation, surgery, chemotherapy) and/or current use of long-term maintenance hormonal or biologic therapy * Age ≥18 years * Elevated fear of recurrence (FCRI severity score ≥16) * MGB/BIDMC Medical Record Number (MRN) Exclusion Criteria: * Self-reported inability to speak and write in English * Undertreated serious mental illness as defined by history of suicidality, psychosis, and/or psychiatric hospitalization in the past year * Inability to access technology and/or sufficient internet to participate virtual groups sessions
References
Publications (2)
- DERIVEDChristie AJ, Bolden C, Park ER, Yeh GY, O'Cleirigh C, Peppercorn J, Denninger JW, Hirschberg AM, Lee H, Markwart M, Siefring E, Mizrach HR, Bullock AJ, Hall DL. Managing, not lessening, uncertainty: a novel mind-body intervention for fear of cancer recurrence. J Cancer Surviv. 2025 Sep 1. doi: 10.1007/s11764-025-01886-2. Online ahead of print. PMID 40887510
- DERIVEDHall DL, Yeh GY, O'Cleirigh C, Wagner LI, Peppercorn J, Denninger J, Hirschberg AM, Lee H, Markwart M, Siefring E, Mizrach HR, Li R, Mian Z, Tsuchiyose E, Wen A, Bullock AJ, Park ER. Pilot Randomized Controlled Trial of IN FOCUS: A Mind-Body Resiliency Intervention for Fear of Cancer Recurrence. Psychooncology. 2024 Nov;33(11):e70026. doi: 10.1002/pon.70026. PMID 39549022