Clinical trial · Interventional
Biocollection in MyeloDysplastic Syndrome (P-MDS)
Biocollection in Patients With Myelodysplastic Syndrome (P-MDS)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Myelodysplastic syndromes (MDS) are chronic myeloid hemopathies characterized by ineffective hematopoiesis (with peripheral cytopenias) and which contrast with a marrow of normal richness. MDS is considered one of the four most common blood diseases. The incidence is estimated at 4,059 cases / year in 2012 with an average age of 78 years in men and 81 years in women (INCA report, Cancers in France in 2015). The incidence increases with lengthening of the lifespan. The main risk of MDS is transformation to acute leukemia in 30 to 40% of cases. Treatment options depend on clinical, hematologic and chromosomal abnormalities. The prognosis is considered to be at low or high risk of developing acute leukemia. This distinction will therefore have an impact on the therapeutic solution (s). MDS exhibit clinical, morphological and genetic heterogeneity. It is therefore necessary to form subgroups of patients to better understand the physiopathogenesis of this pathology. The constitution of a biocollection will make it possible to search for clinical and biological prognostic markers in order to identify patients progressing to acute myeloid leukemia.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Myeloid Leukemia With Multilineage Dysplasia | Acute Myeloid Leukemia with Multilineage Dysplasia | ONTOLOGY_EXACT | 0.98 |
| Chromosome Abnormality | — | UNRESOLVED | — |
| Myelodysplastic Anemia | — | UNRESOLVED | — |
| Myelodysplastic Syndromes | Myelodysplastic Syndrome | ALIAS | 0.90 |
| Myelodysplastic Syndrome With Isolated Del(5Q) | Myelodysplastic Syndrome with del(5q) | ALIAS | 0.90 |
| Myelodysplastic Syndrome With Ring Sideroblasts | Myelodysplastic Syndrome with Ring Sideroblasts | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| description of MDS pzatient cohort | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- MDS follow up
- description
- it is a description MDS patients study
- interventionNames
- Other: description of MDS pzatient cohort
Primary outcomes (1)
- measure
- Cohort MDS: epidemiologic MSD study
- timeFrame
- five years
- description
- MDS study in collecting data
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Major * patient with or suspected of myelodysplastic syndrome (WHO definition) at diagnosis and/or during follow-up, which is managed at the level of the Cancer-Hematology Institute of the Brest CHRU * Presence of biological material collected within the CRB * Patient's consent obtained Exclusion Criteria : * Minor and pregnant woman * Lack of biological material collected within the CRB * Refusal to participate: lack of consent - Unable to consent * Patient under judicial protection: guardianship, curatorship ...
References
Publications (0)
Data not yet available