Clinical trial · Observational
DNA Adductomics for Colorectal Cancer Investigation
Novel DNA Adductomics Methodological Developments for Research in Colon Cancer
NCT04865601CI-TRIAL-00071870adductomicsunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This project seeks to identify DNA-adducts in colon tissue from different groups of patients with CRC scheduled for complete or partial colon resections. Other patients scheduled for resection of the colon serve as controls. In addition, surrogate samples such as white blood cells are investigated for the presense of adducts while blood plasma and urine are investigated for the presense of DNA-repair products.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Familial Adenomatous Polyposis | — | UNRESOLVED | — |
| Hereditary Non-polyposis Colon Cancer | — | UNRESOLVED | — |
| Lynch Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| resectomy of the colon | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (5)
- label
- CRC
- description
- Patient affected by any sporadic colorectal cancer
- interventionNames
- Other: resectomy of the colon
- label
- FAP
- description
- Patients affected by familial adenomatous polyposis coli
- interventionNames
- Other: resectomy of the colon
- label
- HNPCC
- description
- Patient affected by hereditary non polyposis colorectal cancer
- interventionNames
- Other: resectomy of the colon
- label
- Lynch
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with either FAP, Lynch syndrome, other HNPCC, sporadic colorectal cancer, ulcerative colitis or other conditions who are scheduled for whole or partial resection of their colon Exclusion Criteria: * Any condition that makes the investigator or hospital personnel doubt that voluntary participation isfeasible. * Patients who are not able to understand and sign the informed consent form for any reason, including lack of a sufficient period of time to consider their participation. * Patients who are below 18 years of age. * Patients who donated blood to a blood bank within 3 months prior to their operation.
References
Publications (0)
Data not yet available
No reference posted for this study.