Clinical trial · Interventional

Efficiency and Safety of Different Treatment Strategies in Adults With Pituitary Adenomas With Hypothalamic Involvement

NCT04863456CI-TRIAL-00051522unknownN/AClinicalTrials.gov clinicaltrialsPublishedExplore in graph →

Summary

Brief summary (as posted)

Prospective and randomized evaluate efficiency and safety of different treatment strategies for hypothalamus-invading pituitary adenomas (HIPA)

Conditions

Conditions (1)

Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.

Condition (as posted)	Mapped entity	Match	Confidence
Pituitary Adenoma	Pituitary Neuroendocrine Tumor	ALIAS	0.90

Interventions

Interventions (3)

Intervention	Type	Mapped drug	Match
Staged resection	Procedure	—	UNRESOLVED
Subtotal resection followed by stereotactic radiation therapy	Procedure	—	UNRESOLVED
Total resection	Procedure	—	UNRESOLVED

Design

Arms and outcomes

Arms (2)

type
EXPERIMENTAL
label
HIPA group of Puget grade 1
description
the tumor abuting or displacing the hypothalamus in the preoperative MR images
interventionNames
1. Procedure: Total resection
2. Procedure: Staged resection
3. Procedure: Subtotal resection followed by stereotactic radiation therapy
type
EXPERIMENTAL
label
HIPA group of Puget grade 2
description
hypothalamic involvement (the hypothalamus is no longer identifiable) in the preoperative MR images
interventionNames
1. Procedure: Total resection
2. Procedure: Staged resection
3. Procedure: Subtotal resection followed by stereotactic radiation therapy

Primary outcomes (2)

Eligibility

Eligibility (as posted)

Sex: All
Minimum age: 18 Years

Show eligibility criteria text

Inclusion Criteria:

* Suspected symptomatic or progressively growing pituitary adenoma with Hypothalamic Involvement
* Informed consent

Exclusion Criteria:

* No follow-up possible
* Emergency surgery without informed consent

References

Publications (0)

Data not yet available

No reference posted for this study.