Clinical trial · Observational
Genetic Diversity of Toxoplasma Gondii in Cancer Patients
NCT04834076CI-TRIAL-00055945unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
I. Evaluation of T. gondii infection in cancer patients using different serological markers. II. Studying genetic lineages infecting cancer patients in Sohag Governorate to predict clinical course and therapeutic needs using B1 and RE genes.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Toxoplasma Gondii Infection | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ELISA | Diagnostic Test | — | UNRESOLVED |
| PCR | Diagnostic Test | — | UNRESOLVED |
| Sequencing | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Cancer patients
- description
- 50 cancer patients referred to the Oncology Department, Faculty of medicine, Sohag University.
- interventionNames
- Diagnostic Test: ELISA
- Diagnostic Test: PCR
- Diagnostic Test: Sequencing
- label
- Healthy controls
- description
- 50 healthy controls will be recruited in the study.
- interventionNames
- Diagnostic Test: ELISA
- Diagnostic Test: PCR
- Diagnostic Test: Sequencing
Primary outcomes (2)
- measure
- Isolation and genotyping of T. gondii from blood of Cancer patients in Sohag Governorate, Egypt using PCR and DNA sequencing of Toxoplasma gondii B1 & RE genes.
- timeFrame
- up to 1 year
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Year
Show eligibility criteria text
Inclusion Criteria: * Hematologic cancers on treatment * Solid Cancers on treatment Exclusion Criteria: * Patients with other immune compromise states eg. DM, autoimmune diseases * Patients who are HIV positive
References
Publications (1)
- DERIVEDFadel EF, Tolba MEM, Ahmed AM, El-Hady HA. Serological and molecular detection of Toxoplasma Gondii among cancer patients in Sohag, Upper Egypt: a case-control study. Sci Rep. 2025 Feb 12;15(1):5236. doi: 10.1038/s41598-025-88680-3. PMID 39939648