Clinical trial · Interventional
A Prehabilitation Program to Boost Postoperative Functional Capacity in Surgical Lung Cancer Patients
A Prehabilitation Program to Boost Postoperative Functional Capacity in Surgical Lung Cancer Patients: a Randomized Controlled Trial
NCT04826835CI-TRIAL-00072787unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research study is evaluating a prehabiliation intervention designed to improve postoperative functional capacity (measured by 6-minure walking distance) in individuals undergoing lung resection for cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Health education control | Behavioral | — | UNRESOLVED |
| Prehabilitation intervention | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Prehabilitation intervention
- description
- Participants in the intervention group will follow a 2-week prehabilitation program before lung resection.
- interventionNames
- Behavioral: Prehabilitation intervention
- type
- ACTIVE_COMPARATOR
- label
- Health education control
- description
- Participants in the control group will receive health education classes during 2 weeks before lung resection.
- interventionNames
- Behavioral: Health education control
Primary outcomes (1)
- measure
- Change from baseline 6-minute walking distance from baseline to 3-month post-surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 45 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients who are diagnosed of stage I, II, or IIIA Non-small-cell lung carcinoma (NSCLC) diagnosis, with or without pre-operative histologic confirmation 2. Patients scheduled to undergo lung resection surgery at least two weeks from recruitment 3. Patients with a Eastern Cooperative Oncology Group (ECOG) score of 0 or 1 at recruitment 4. Patients with no evidence of recurrent or progressive disease 5. Patients aged 45-80 years 6. Patients able to communicate in Cantonese, Mandarin, or English 7. Patients is absence of any cognitive impairment 8. Patients with a score of 6 minutes walking test (6MWT) ≤ 500 meters at baseline. \[rationale: a threshold value of 500 meters preoperative 6MWT predicts a higher risk of postoperative complications and prolonged LOS after lung resection\] 9. Engagement in less than 150 minutes of moderate aerobic activity per week in the past 3 months Exclusion Criteria: 1. Patients who had engaged in at least 150 minutes of moderate aerobic activity or 75 minutes of vigorous aerobic activity per week in the past three months 2. Presence of another concurrent, actively treated malignancy 3. Presence of chronic obstructive pulmonary disease 4. Presence of significant comorbidities that impede ability to engage in exercise, such as congestive heart failure, orthopedic disorders of the lower limbs, respiratory failure, or the need for portable oxygen therapy for activities of daily living 5. Not having a smart device to receive WhatsApp messages
References
Publications (0)
Data not yet available
No reference posted for this study.