Clinical trial · Interventional
Endoscopic Versus Percutaneous Biliary Drainage for Resectable Pancreatic Head Cancer
Endoscopic Versus Percutaneous Biliary Drainage for Resectable Pancreatic Head Cancer With Hyperbilirubinemia and Impact on Pancreaticoduodenectomy: A Prospective Cohort Study
NCT04823832CI-TRIAL-00051025completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients with potentially resectable pancreatic head cancer and high bilirubin level, were stratified into two equal groups according to the method of biliary drainage: endoscopic stenting or percutaneous drainage.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Obstructive Jaundice | — | UNRESOLVED | — |
| Pancreatic Head Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| pancreaticoduodenectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- ERCP group
- description
- endoscopic retrograde cholangiopancreaticography with plastic stent insertion
- interventionNames
- Procedure: pancreaticoduodenectomy
- type
- ACTIVE_COMPARATOR
- label
- PTD group
- description
- ultrasound guided percutaneous transhepatic catheter insertion
- interventionNames
- Procedure: pancreaticoduodenectomy
Primary outcomes (2)
- measure
- number of participants with operative difficulties as assessed by the operating surgeon
- timeFrame
- up to 6 hours at the time of surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with malignant obstruction of the distal common bile duct e.g. adenocarcinoma of the pancreatic head or periampullary tumor * Hyperbilirubinemia, total bilirubin level more than 10 mg/dL * Cholangitis, pruritis, coagulopathy, nausea and anorexia Exclusion Criteria: * Patients with advanced disease * metastatic disease * Patients undergoing neoadjuvant therapy
References
Publications (0)
Data not yet available
No reference posted for this study.