Clinical trial · Observational
Molecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural Mesothelioma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Malignant pleural mesothelioma (MPM) is a rare pleural cancer, which could be primary or secondary to an asbestos exposure. To enhance our knowledge of this rare disease, an exploration of genetic and tumor mechanism is mandatory. One of the principal difficulty is to harvest sufficient tumour pieces to perform multi-omics analysis. The goal of the SCITH-MESO study is to harvest larges pieces of tumour during a routine surgical procedure of MPM diagnosis by mean of pleural biopsies during VATS surgery. Operating samples will increase a tissue bank collection (CRB).
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gene Abnormality | — | UNRESOLVED | — |
| Mesothelioma, Malignant | Malignant Mesothelioma | ALIAS | 0.90 |
| Pleural Mesothelioma | Pleural Mesothelial Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| PLEURAL BIOCOLLECTION OF MALIGNANT PLEURAL MESOTHELIOMA | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- PLEURAL BIOCOLLECTION OF MALIGNANT PLEURAL MESOTHELIOMA
- description
- All patient with suspected malignant pleural mesothelioma requiring surgical biopsy after validation in oncologic multidisciplinary board will be included. During a standardized routine procedure of pleural biopsy by mean of general anesthesia and video thoracoscopic approach, 3 - 5 biopsies are realized. During this procedure, blood samples are collected and a piece of biopsy will be used for the constitution of a specific bio collection in the CRB (centre de ressources biologiques).
- interventionNames
- Genetic: PLEURAL BIOCOLLECTION OF MALIGNANT PLEURAL MESOTHELIOMA
Primary outcomes (1)
- measure
- For patients with MPM, blood samples are collected and a piece of biopsy will be used for the constitution of a specific bio collection in the CRB (centre de ressources biologiques).
- timeFrame
- day 1 (day of chirurgie)
- description
- For patients with MPM, blood samples are collected and a piece of biopsy will be used for the constitution of a specific bio collection in the CRB (centre de ressources biologiques).
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 95 Years
Show eligibility criteria text
Inclusion Criteria: * age \>18 * suspected MPM requiring VATS biopsy after multidisciplinary oncologic board validation * patient able to understand study objectives and able to give an informed consent * patient affiliated to an healthcare society. Exclusion Criteria: * pregnancy * mental disease, psychiatric disorder * patient under protection regimen
References
Publications (0)
Data not yet available