Clinical trial · Observational
Developing Novel Circulating Epigenetic Biomarkers for Early Detection of Lung Cancer
NCT04814407CI-TRIAL-00078049recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators aim to identify novel circulating methylated biomarkers for early lung cancer detection as well as to develop new technologies that are clinically applicable with high sensitivity and specificity.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood-derived DNA methylation detection | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Lung cancer patients
- description
- Patients age over 20, with suspected or confirmed diagnosis of lung cancer.
- interventionNames
- Diagnostic Test: Blood-derived DNA methylation detection
- label
- Indeterminate subjects
- description
- Subjects who had indeterminate sub-centimeter pulmonary nodules or ground glass opacities discovered by computed tomography.
- interventionNames
- Diagnostic Test: Blood-derived DNA methylation detection
- label
- Control subjects
- description
- Non-cancer patients including healthy volunteers, chronic inflammatory airway diseases such as chronic obstructive airway disease, asthma, and bronchiectasis, etc.
- interventionNames
- Diagnostic Test: Blood-derived DNA methylation detection
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: * Subjects suspected or confirmed diagnosis of lung cancer. * Subjects who had indeterminate sub-centimeter pulmonary nodules or ground glass opacities discovered by computed tomography. * Non-cancer subjects: including healthy volunteers and chronic inflammatory airway diseases such as chronic obstructive airway disease, asthma, and bronchiectasis, etc. * Subjects age over 20. Exclusion Criteria: * Pregnancy. * Subjects with HIV infection. * Unable to or unwilling to give informed consent.
References
Publications (0)
Data not yet available
No reference posted for this study.