Clinical trial · Interventional
"No-Touch" Radiofrequency Ablation for Small Hepatocellular Carcinoma (≤ 3cm): A Prospective Multicenter Study
"No-Touch" Radiofrequency Ablation Using Octopus Electrodes and Combined RF Energy Delivery Mode for Small Hepatocellular Carcinoma (≤ 3cm): A Prospective Multicenter Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Early termination d/t overlap with a new, extended protocol study.
Summary
Brief summary (as posted)
This study is a prospective multicenter study of the duration of treatment, the success rate, the frequency of complications, and the local recurrence rate of 12 months when Radio-frequency ablation therapy is performed for the treatment of HCC using the 'No touch' technique as a combined high-frequency transmission mode with Octopus electrodes. It aims to evaluate through. In addition, the results obtained from this prospective study were as follows: 1) Patients who underwent Radio-frequency ablation therapy by puncturing an existing tumor, and 2) Patients who underwent microwave ablation during the study period. The secondary goal is to evaluate which method is more effective in reducing the treatment time and recurrence rate compared to.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Microwave Ablation | — | UNRESOLVED | — |
| Radiofrequency Ablation | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| "No-Touch" Radiofrequency Ablation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- No touch radiofrequency ablation
- description
- A total of 150 patients who have decided to participate in the study will be included, and prospective study will be performed to these patients for radio-frequency ablation using octopus electrodes, combined high-frequency transmission mode, and the 'No touch' technique.
- interventionNames
- Procedure: "No-Touch" Radiofrequency Ablation
Primary outcomes (1)
- measure
- Local tumor progression (LTP) rate
- timeFrame
- 12 months after RFA
- description
- No. of participants with LTP/ No. of participants receiving RFA
Secondary outcomes (2)
- measure
- Intrahepatic distant recurrence (IDR) rate
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * Agree to the protocol's requirements and submit a consent form * 20 years old-85 years old * Child-Pugh Class A or B7 * Among patients with cirrhosis, patients with hepatocellular carcinoma having a size of 1 cm-3 cm suspected of MDCT or MRI performed within 60 days are considered for radio-frequency ablation * Patients who do not have a history of treatment for previous hepatocellular carcinoma, or who have a history of treatment for previous hepatocellular carcinoma, if recurrence has not been confirmed for at least 2 years after treatment Exclusion Criteria: * the number of liver tumors is 3 or more * the maximum size of the tumor exceeds 3 cm * diffuse infiltrative type * the tumor adheres to the portal vein or hepatic vein or biliary tract of 5 mm or more * patients with previous medical history of hepatocellular cancer who have recurrent hepatocellular cancer within 2 years * the tumor is not visible even under CEUS-fusion image guidance * Child-Pugh class B8 or C * in case of invasion of liver vessels due to malignant hepatocellular carcinoma * severe coagulopathy * multiple distant metastasis * the situation where the probability of obtaining appropriate data suitable for the research purpose is very low
References
Publications (0)
Data not yet available