Clinical trial · Interventional
Optimisation of Potential Dental Implant Sites Protection for Rehabilitation in Patients With Head and Neck Cancer: Impact of Virtual Implants Visualisation on Dosimetry (OPPIDOM)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): organisationnal reason
Summary
Brief summary (as posted)
This is a monocentric, non-randomized, prospective, in silico feasibility study conducted by Strasbourg Europe Cancerology Institute. The purpose of this study is to evaluate the optimisation of potential dental implant sites protection, without degrading tumor volume coverage, through designation of potential dental implant sites before volume delineation and dosimetry calculations in patients with oropharyngeal or oral cavity squamous cell carcinoma treated by radiotherapy.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Oral Cavity Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Oropharyngeal Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Squamous Cell Carcinoma of Head and Neck | Head and Neck Squamous Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Optimisation of dental implant sites protection from irradiation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Patients with oral cavity or oropharyngeal squamous cell carcinoma
- interventionNames
- Other: Optimisation of dental implant sites protection from irradiation
Primary outcomes (1)
- measure
- Identification of optimal scanner allowing to obtain the greater number of patients with every designated implant sites that are protected
- timeFrame
- At baseline
- description
- Condition of dental implant sites protection (i.e. with minimal implantation risk, Dmax \< 40 Gy), without degrading the coverage of planned targeted volume (≥ 95% of volume receiving 95 % of prescribed dose)
Secondary outcomes (6)
- measure
- Acute toxicity evaluation
- timeFrame
- every weeks during radiotherapy
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients must be ≥ 18 years old * Performance Status 0 to 2 * Histologically-confirmed diagnosis of : infiltrating squamous cell carcinoma of the oral cavity or oropharynx * Indication for an exclusive radiotherapy or post-surgery radiotherapy, with or without chemotherapy * Indication for a radiotherapy of lymph node areas * Partial or complete toothlessness requiring rehabilitation * Signed informed consent from the patient Exclusion Criteria: * History of head and neck radiotherapy * Partial mandibulectomy * Retarded wound healing or trismus impairing radiological guide preparation * Patient refusing the study * Pregnant women
References
Publications (0)
Data not yet available