Clinical trial · Interventional
Study on the Peristaltic Direction of GI Anastomosis in Roux-en-Y Reconstruction
A Single Center Randomized Prospective Study on the Peristaltic Direction of Gastrointestinal Anastomosis in Roux-en-Y Reconstruction After Distal Curative Gastrectomy for Gastric Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is intending to provide the optimal procedures of the peristaltic direction of gastrointestinal anastomosis in Roux-en-Y reconstruction after distal curative gastrectomy for gastric cancer, which can provide the best operation mode of Roux-en-Y anastomosis in digestive tract reconstruction during distal gastrectomy for reducing postoperative complications and improving quality of life for patients.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Peristaltic Direction | — | UNRESOLVED | — |
| Roux-en-Y Gastrointestinal Anastomosis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Direction procedure of gastrointestinal anastomosis in Roux-en-Y reconstruction | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Antiperistaltic direction of gastrointestinal anastomosis in Roux-en-Y reconstruction group
- description
- The isoperistaltic anastomosis represents the peristalsis direction of remnant stomach and jejunal efferent loop was consistent.
- interventionNames
- Procedure: Direction procedure of gastrointestinal anastomosis in Roux-en-Y reconstruction
- type
- ACTIVE_COMPARATOR
- label
- Isoperistaltic direction of gastrointestinal anastomosis in Roux-en-Y reconstruction group
- description
- The antiperistaltic anastomosis represents the peristalsis direction of remnant stomach and jejunal efferent loop was opposite.
- interventionNames
- Procedure: Direction procedure of gastrointestinal anastomosis in Roux-en-Y reconstruction
Primary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * 1\) Pathological examination confirmation the adenocarcinoma of stomach before surgery * 2\) Physical conditions compliance with the requirements for curative gastrectomy * 3\) Consent to undergo the D2 lymphadenectomy, and the dissected proportion of stomach no less than 2/3 * 4\) Comply with the protocol during the whole study period * 5\) No neoadjuvant therapy administration * 6\) Sign informed consent and permission of withdraw in the whole study period * 7\) Consent to provide the tissue specimens after surgery for this study * 8\) Estimation the overall survival after surgery no less than 6 months * 9\) No anesthesia or operation contraindication disease * 10\) cT1-4N0-2M0 stage demonstration by CT and endoscopic ultrasonography examinations * 11\) Negative cytological detection in operation * 12\) No seriously concomitance's diseases * 13\) Karnofsky Performance Scores (KPS) more than 60 * 14\) Examined lymph node count no less than 16 Exclusion Criteria: * 1\) Women during pregnant stage and breast-feed stage * 2\) Women of childbearing age without any contraceptive measures * 3\) Severe congestive heart failure, frequent arrhythmia, or myocardial infarction within 12 months * 4\) Immunosuppressive therapists for organ transplantation * 5\) Seriously uncontrolled recurrent infection * 6\) other malignant tumors * 7\) No abilities of self-knowledge or mental disorders * 8\) Participating in other clinical trials * 9\) Siewert I and II esophagogastric junction tumors * 10\) Serious internal diseases obstruction surgery
References
Publications (0)
Data not yet available