Clinical trial · Interventional
Yoga on QOL Physiological Distress&Fatigue, on Patients Affected by Breast Cancer in Adjuvant Radiotherapy
Monocentric, Randomized Clinical Trial About the Effect of Yoga Practice on QOL, Physiological Distress and Fatigue, on Patients Affected by Breast Cancer Undergoing Adjuvant Radiotherapy
NCT04775290CI-TRIAL-00050378YogaRTunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study aims to investigate, through serial measurements of some biomarkers, the potential mechanisms through which yoga impacts on QOL and fatigue.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Fatigue | — | UNRESOLVED | — |
| Female Breast Cancer | — | UNRESOLVED | — |
| Physiological Stress | — | UNRESOLVED | — |
| Quality of Life | — | UNRESOLVED | — |
| Radiotherapy; Complications | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Yoga lessons | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Arm Yoga (YG)
- description
- Patients assigned to the YG arm participate in yoga classes
- interventionNames
- Behavioral: Yoga lessons
- type
- NO_INTERVENTION
- label
- Arm control (CG)
- description
- Patients assigned to the CG arm will follow the normal course of radiotherapy.
Primary outcomes (1)
- measure
- Change of physiological distress
- timeFrame
- up to 32 months
- description
- Evaluation of the efficacy of yoga on reduction of physiological distress after the end of radiotherapy, measured via Short Form 36 (SF-36), Pittsburgh Sleep Quality Index (PSQI) and Quality of life questionnaire Core30 (QLQ-C30) questionnaire, and physiological functions (cortisol, blood sampling with proinflammatory markers evaluation) in stage 0-III breast cancer patients
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Women with stage 0-III breast cancer who have undergone adjuvant daily radiotherapy for 5 weeks in Istituto Scientifico Romagnolo per lo studio e la cura dei Tumori (IRST) Department of Radiation Oncology of Meldola. Exclusion Criteria: * Patients with documented diagnosis of mental disorders (eg Schizophrenia) * Patients with stage IV disease * Patients with active or non-canalised deep vein thrombosis * Patients not undergoing surgery for the basic oncological disease * Patients with mobility problems (eg unable to get up from the chair) * Patients who have practiced yoga or are practicing yoga in the 6 months before the cancer diagnosis. * Patients diagnosed with lymphedema
References
Publications (1)
- DERIVEDMesser S, Oeser A, Wagner C, Wender A, Cryns N, Scherer RW, Mishra SI, Monsef I, Holtkamp U, Andreas M, Brockelmann PJ, Ernst M, Skoetz N. Yoga for fatigue in people with cancer. Cochrane Database Syst Rev. 2025 May 27;5(5):CD015520. doi: 10.1002/14651858.CD015520. PMID 40421669