Clinical trial · Interventional
Effectiveness of MyCancerGene to Optimize Genetic Testing Outcomes
NCT04774445CI-TRIAL-00085672MyCancerGeneactive not recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This protocol aims to evaluate the efficacy of a theoretically and stakeholder informed patient-centered genetic Interactive Health Communication Application to increase patient understanding of, and affective and behavioral responses to genetic testing. The study investigators hypothesize that the intervention will be associated with increases in knowledge, decreases in distress, increases in communication with relatives and health care providers, and increases in performance of risk reducing health behaviors.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Genetic Predisposition | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MyCancerGene | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Intervention Group
- description
- Individuals randomized to this arm will receive immediate access to the Interactive Health Communication Application.
- interventionNames
- Behavioral: MyCancerGene
- type
- NO_INTERVENTION
- label
- Usual Care Group
- description
- Individuals randomized to this arm will receive the standard clinical practice.
Primary outcomes (2)
- measure
- The KnowGene Scale
- timeFrame
- Baseline - 18 Months
- description
- Change in Knowledge. Score Range = 0-16. Higher score = Better outcome
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * 18 years of age or older * English Speaking * Male or Female * Internet and/or mobile access * Previously received clinical genetic counseling and testing for hereditary cancer syndromes (up to 60 days prior to recruitment) Exclusion Criteria: •No internet and/or mobile access
References
Publications (1)
- DERIVEDChavez-Yenter D, Fetzer D, Egleston B, Domchek S, Fleisher L, Wagner LI, Wen KY, Karpink K, Gutstein L, Posen S, Selmani E, McLeod B, Anantharajah A, Brown S, Cacioppo C, Cappadocia J, Ebrahimzadeh JE, Falcone D, Howe S, Langer C, McCarthy-Wood B, Weinberg M, Bradbury AR. The MyCancerGene study: a hybrid type 1 effectiveness-implementation randomized study comparing a patient-centered digital genetic health portal to usual care after receipt of cancer genetic testing. BMC Cancer. 2025 Oct 24;25(1):1642. doi: 10.1186/s12885-025-14968-2. PMID 41136924