Clinical trial · Interventional
Immunologic Effect of Fraction of Inspired Oxygen
Immunological Effect of Intraoperative Fraction of Inspired Oxygen in Patients Undergoing Major Abdominal Cancer Surgery
NCT04772794CI-TRIAL-00050344unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
During anesthesia and surgery, oxygen is routinely administered to all patients. Inspired oxygen concentrations, however, vary between 30% - 100% and oxygen is often administered in a seemingly random manner.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Immune System | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| fraction of inspired oxygen | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- hyperoxygenation group
- description
- Intraoperative administration of a mixture of 80% oxygen and 20% air
- interventionNames
- Other: fraction of inspired oxygen
- type
- PLACEBO_COMPARATOR
- label
- control group
- description
- intraoperative administration of 30% oxygen and 70% air
- interventionNames
- Other: fraction of inspired oxygen
Primary outcomes (2)
- measure
- changes in serum level of interlukin 6
- timeFrame
- before operation (0), 1st, 3rd, and 7th days postoperative
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * candidates for abdominal cancer surgeries Exclusion Criteria: * Patients with chronic diseases, such as chronic obstructive pulmonary disease or pneumonia, * body mass index (BMI) \>35 kg/m2, * severe malnutrition (albumin \<3), * leukopenia (white blood cell \<4,000 g/dL), * surgery within the previous 30 days and * O2 saturation \< 90%, as measured using a pulse oximeter
References
Publications (0)
Data not yet available
No reference posted for this study.