Clinical trial · Interventional
Quantitative MRI of Bone Marrow in Patients With Acute Lymphoblastic Leukemia
Clinical Pilot Study of Quantitative MRI Assessment of Bone Marrow in Patients With Acute Lymphoblastic Leukemia and Patients Without Hematopoietic Disorders, From 6 to 18 Years Old
NCT04767165CI-TRIAL-00064542unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study is aimed at assessing changes in the bone marrow of patients from 6 to 18 years old with a diagnosis of acute lymphoblastic leukemia during chemotherapy. Patients of the same age without hematological diseases will be recruited as a control group.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Leukemia | Acute Leukemia | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MRI | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (4)
- measure
- Dynamics of Bone marrow fat fraction
- timeFrame
- Point 1. Before the start of therapy - the starting point.
- description
- Dynamics of Bone marrow fat fraction by mDixon-quant (%)
- measure
- Dynamics of Bone marrow fat fraction
- timeFrame
- Point 2. 15 ± 3 days after the start of the therapy.
- description
- Dynamics of Bone marrow fat fraction by mDixon-quant (%)
- measure
- Dynamics of Bone marrow fat fraction
- timeFrame
- Point 3. 36 ± 3 days after the start of the therapy.
- description
- Dynamics of Bone marrow fat fraction by mDixon-quant (%)
- measure
- Dynamics of Bone marrow fat fraction
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 6 Years
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. patients from 6 to 18 years old 2. diagnosis of acute lymphoblastic leukemia during chemotherapy 3. patients of the same age without hematological diseases Exclusion Criteria: 1. patients less then 6, and older then 18 years old 2. patients who cannot perform the study MRI without general anesthesia
References
Publications (0)
Data not yet available
No reference posted for this study.