Clinical trial · Interventional
Cardiorespiratory Fitness in Children and Adolescents After Cancer Treatment.
Effects of a Physical Activity Program On Cardiorespiratory Fitness in Children and Adolescents folloWing Acute cancER Treatment: a Randomized Controlled Trial
NCT04765020CI-TRIAL-00111680POWERrecruitingPhase 2 / Phase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The POWER-study is a two-arm exercise intervention study for pediatric patients following acute cancer treatment. This clinical trial will investigate the effects of a 12-week moderate to high-intensity exercise program on cardiorespiratory fitness in children and adolescents beginning 6 weeks after completion of acute cancer treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| All Types of Pediatric Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Experimental: moderate to high-intensity exercise | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Intervention group
- description
- 12 weeks moderate to high-intensity exercise program
- interventionNames
- Behavioral: Experimental: moderate to high-intensity exercise
- type
- NO_INTERVENTION
- label
- Control group
- description
- exercise recommendations
Primary outcomes (1)
- measure
- Change in maximal oxygen uptake (VO2peak, ml/kg/min) from Baseline to T1 (end of intervention/12-weeks post randomization) between the two study groups, assessed in a maximal incremental exercise test (CPET) on a bicycle ergometer.
- timeFrame
- At Baseline T0: 6 weeks following acute cancer treatment, T1: after 12 weeks of intervention, T2 (Follow up): after 12 weeks after end of intervention = 24 weeks after study inclusion
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 7 Years
- Maximum age
- 23 Years
Show eligibility criteria text
Inclusion Criteria: * Children and adolescents between 7 and 23 years of age * Completion of acute cancer treatment and receiving follow-up care in Krefeld (Helios Hospital Krefeld) * 6 weeks post cancer-treatment * Signed informed consent (Parents and Patient) Exclusion Criteria: * \<7 years of age, \>23 years of age * Medical condition that limits participation in one of the study arms * Inability to follow the training-protocol * Inability to carry out the spiroergometry on a cycle ergometer
References
Publications (0)
Data not yet available
No reference posted for this study.