Clinical trial · Interventional
The TOTOM Trial: Tai Chi to Optimize Transplant Outcomes for Multiple Myeloma
NCT04760405CI-TRIAL-00079876completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The current proposal aims to test the feasibility of immune function analysis for Tai Chi Easy (TCE) intervention in multiple myeloma (MM) patients undergoing autologous stem cell transplantation (ASCT) with concurrent exploration of health related quality of life (HRQOL).
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Multiple Myeloma | Multiple Myeloma | CURATED_EXACT | 0.92 |
| Stem Cell Transplant Complications | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Tai Chi Easy | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Tai Chi Easy Intervention
- description
- Tai Chi Easy: TCE is a standardized protocol used in several prior studies. TCE has been manualized and has a formal training program for instructors. The protocol is taught as a series of repeated and simple-to-learn movements. Patients will receive two 30-minute small group training sessions (Via Zoom) within 7 days of their scheduled transplant. After the training has been completed the participant will be provided with written (via manual) and electronic (DVD, MP3 file download) materials to continue with self-direct practice throughout the duration of the study.
- interventionNames
- Other: Tai Chi Easy
Primary outcomes (12)
- measure
- Determine natural killer cell phenotype
- timeFrame
- Baseline
- description
- Determine natural killer (NK) phenotype through peripheral blood analysis
- measure
- Determine natural killer cell phenotype
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Diagnosis of Multiple Myeloma planned to undergo bone marrow transplant 2. 18 years or older 3. English speaking 4. General proficiency to read/write in English 5. Able to attend TCE training session per study protocol 6. ECOG performance status 0-1 7. Able to return to study center for routine post-transplant follow up (approximately Day 30 and Day 100) Exclusion Criteria: 1. Currently performs Tai Chi, QiQong, or Yoga at least once weekly or more 2. Syncopal event in prior 60 days 3. Concurrent major depressive disorder or anxiety disorder (DSMIV) as determined by treating provider 4. Chronic dizziness or vestibular disorders 5. History of recurrent falls (\>2 in the prior year) 6. Grade 3 or greater neuropathy 7. Grade 3 or greater spinal fracture
References
Publications (0)
Data not yet available
No reference posted for this study.