OPPIuM Technique and Myolysis With Diode Laser Dwls

PURPOSE OF THE STUDY The study aims to examine the feasibility and effectiveness of the OPPIuM technique combined with myolysis using the DWLS diode laser. In addition, to evaluate the reduction of myoma volume and the extent of uterine bleeding with myolysis to improve women's quality of life and avoid resectoscope hysteroscopy for a G2 MIOMA, which may lead to an increase in intraoperative surgical risks and long-term complications. POPULATION 35 patients aged between 18 and 48 years with clinical and/or ultrasound diagnosis of uterine fibromatosis, belonging to the Endometriosis/Pelvic Chronic Pain Centre of the Complex Operating Unit of Gynecology of the University Polyclinic of Monserrato and other centers involved in the study. To be eligible for inclusion, patients with ultrasound and hysteroscopic diagnosis of a single submucosal myoma, partially intramural (G1 or G2) ≤ 3 cm, must present symptoms such as abnormal uterine bleeding and pelvic pain, for which surgical treatment was scheduled. INCLUSION CRITERIA * Women between 18 and 48 years old * Diagnosis of symptomatic uterine fibromatosis (abnormal uterine bleeding and/or pelvic pain) with single fibroma ≤ 3 cm G1 or G2. EXCLUSION CRITERIA Patients who cannot provide written informed consent or follow the procedures set out in the protocol. * Patients with malignant neoplasms or serious systemic diseases * Patients with multiple fibroids or single \> 3 cm * Asymptomatic patients * Patients with other uterine or related diseases * Patients seeking a pregnancy. INTERVENTION STRATEGY AND INSTRUMENTS A total of 35 women will initially be included in the study, of which: Patients will undergo the following assessments: * Collection of physiological, pathological, and pharmacological anamnesis * Collection of diagnostic tests (ultrasound) and staging of the underlying disease (uterine fibromatosis) * Completion of the PBAC questionnaire * Transvaginal ultrasound * Office diagnostic hysteroscopy with OPPIuM and Myolysis * Possible resectoscope hysteroscopy or laser myomectomy in narcosis.

Sex

Female

Minimum age

18 Years

Maximum age

48 Years

Inclusion Criteria:

* Women between 18 and 48 years old
* Diagnosis of symptomatic uterine fibromatosis (abnormal uterine bleeding, pelvic pain and/or infertility) with single fibroma ≤ 3 cm G1 or G2.

Exclusion Criteria:

* Patients who are unable to provide written informed consent or to follow the procedures set out in the protocol.
* Patients with malignant neoplasms or serious systemic diseases
* Patients with multiple fibroids or single \> 3 cm
* Asymptomatic patients
* Patients with other uterine or related diseases
* Patients seeking for a pregnancy.

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