Clinical trial · Observational
A Study of Noninvasive Methods to Evaluate Skin and Mucosal Conditions
Noninvasive Assessment of Muco-cutaneous Lesions In Vivo
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to find out whether using noninvasive methods to study the appearance of lesions can improve diagnostic accuracy before a biopsy is required and help guide treatment planning. The database created to store these images is called an Image Repository, and it will be used to support clinical practice, teaching and training, and future research.The High-resolution OCT (Apollo Medical Optics) device ApolloVue® S100 Image System (medical device Class II) can provide both cross-sectional and en-face images with cellular information.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Mucosal Lesion | — | UNRESOLVED | — |
| Skin Lesion | — | UNRESOLVED | — |
Interventions
Interventions (8)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 3-dimensional total body photography | Diagnostic Test | — | UNRESOLVED |
| Confocal microscopy | Diagnostic Test | — | UNRESOLVED |
| Dermoscopic imaging | Diagnostic Test | — | UNRESOLVED |
| Electrical impedance spectroscopy | Diagnostic Test | — | UNRESOLVED |
| Hyperspectral imaging | Diagnostic Test | — | UNRESOLVED |
| Optical Coherence Tomography imaging | Diagnostic Test | — | UNRESOLVED |
| Patient self-imaging | Diagnostic Test | — | UNRESOLVED |
| Ultrasound | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Participants with muco-cutaneous lesions
- description
- Participants will have muco-cutaneous lesions for non-invasive evaluation (including normal skin or mucosa and benign lesions) and will be identified by their physicians or fellows during routine clinical care.
- interventionNames
- Diagnostic Test: Dermoscopic imaging
- Diagnostic Test: 3-dimensional total body photography
- Diagnostic Test: Confocal microscopy
- Diagnostic Test: Optical Coherence Tomography imaging
- Diagnostic Test: Ultrasound
- Diagnostic Test: Hyperspectral imaging
- Diagnostic Test: Electrical impedance spectroscopy
- Diagnostic Test: Patient self-imaging
Primary outcomes (1)
- measure
- Collect images of untreated and treated neoplastic and non-neoplastic muco-cutaneous conditions
- timeFrame
- 7 years
- description
- The primary outcome of this study is to collect images from varied images devices with the dermatology service and to create an effective mechanism for the storage and dissemination of the resultant images for research purposes.
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * All ages * Patients with a muco-cutaneous lesion(s) amenable to imaging by non-invasive tools * Healthy volunteer subjects * Ability to give informed consent or in the case of pediatric patients, assent and consent from the parent/guardian Exclusion Criteria: * Allergy or intolerance to ultrasound gel or mineral oil used for imaging * Patients who are not able to comply with imaging procedure
References
Publications (0)
Data not yet available