Clinical trial · Interventional
Bioactive Glass or Allogenic Bone in Pediatric Bone Cysts
A Randomized Clinical Trial Comparing Curettage With Allogenic Bone Grafting and Curettage With Bioactive Glass Filling in Children With Bone Cysts CYSTS
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Finnish Paediatric Orthopedic Study Group will perform a prospective, randomized, multicenter, clinical trial comparing two bone substitutes (allograft and bioactive glass, BonAlive®) in treating bone cysts in children (18 years or younger). The trial is carried out in five University Hospitals (Turku, Helsinki, Tampere, Oulu, Kuopio) in Finland.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bone Cysts | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Bioactive glass | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Bioactive glass
- description
- 20 bone cysts (in 20 patients) are filled with bioactive glass
- interventionNames
- Device: Bioactive glass
- type
- ACTIVE_COMPARATOR
- label
- Allogenic bone
- description
- 20 bone cysts (in 20 patients) are filled with allogenic bone
- interventionNames
- Device: Bioactive glass
Primary outcomes (10)
- measure
- Recurrence rate
- timeFrame
- through study completion, average 2 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Year
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Suspected aneurysmatic bone cyst in all areas, not spinal. 2. Other large simple bone cyst in load bearing areas 3. Simple or aneurysmal bone cyst and a pathological fracture in non load-bearing areas Exclusion Criteria: 1. Malignancy 2. Bone marrow disease 3. Other than aneurysmatic or simple bone cyst 4. A secondary aneurysmal bone cyst (ABC associated with another underlying lesion)
References
Publications (0)
Data not yet available