Clinical trial · Interventional
ESP in Breast Surgery Due to Cancer
Effectiveness of the Erector Spinae Plane Block in Patients Undergoing Breast Surgery Due to Cancer
NCT04726878CI-TRIAL-00054952completedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients scheduled for breast surgery due to cancer. Each patient will be treated with intravenous (i.v.) oxycodone - patient-controlled analgesia (PCA). Patients will be allocated to one of three groups: erector spinae plane (ESP) block, sham block, controlled group.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anesthesia, Local | — | UNRESOLVED | — |
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Pain, Acute | — | UNRESOLVED | — |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Erector spinae plane block | Procedure | — | UNRESOLVED |
| General anesthesia | Procedure | — | UNRESOLVED |
| Oxycodone | Drug | — | UNRESOLVED |
| paracetamol | Drug | — | UNRESOLVED |
| Patient-controlled analgesia | Procedure | — | UNRESOLVED |
| Sham block | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- PLACEBO_COMPARATOR
- label
- Controlled
- description
- Standard care without regional block. General anesthesia. After the end of the surgery, the patient-controlled analgesia with oxycodone.
- interventionNames
- Procedure: General anesthesia
- Procedure: Patient-controlled analgesia
- Drug: Oxycodone
- Drug: paracetamol
- type
- EXPERIMENTAL
- label
- ESP block
- description
- After the induction of general anesthesia, before the beginning of the surgery, the erector spinae plane block with 0.375% ropivacaine will be performed. Then, the patient will be treated as in the controlled group.
- interventionNames
- Procedure: Erector spinae plane block
- Procedure: General anesthesia
- Procedure: Patient-controlled analgesia
- Drug: Oxycodone
- Drug: paracetamol
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Elective surgery of breast due to cancer * obtained consent Exclusion Criteria: * the lack of consent * the surgery of two breasts * reoperation of the same breast * previous participation in the study * coagulopathy * allergy to morphine and local anesthetics * depression, antidepressant drugs treatment * epilepsy * usage of painkiller before surgery * addiction to alcohol or recreational drugs
References
Publications (1)
- DERIVEDWiech M, Piwowarczyk P, Mieszkowski M, Tuyakov B, Pituch-Sala K, Czarnik T, Kurylcio A, Czuczwar M, Borys M. The quality of recovery after erector spinae plane block in patients undergoing breast surgery: a randomized controlled trial. BMC Anesthesiol. 2022 Jul 14;22(1):222. doi: 10.1186/s12871-022-01760-z. PMID 35836116