Clinical trial · Interventional
AQCS for Detection of Early Cancer and Precancerous Lesions on Upper Gastrointestinal Tract
Computer-aided Real-time Automatic Quality-control System for Detection of Early Cancer and Precancerous Lesions on Upper Gastrointestinal Tract: a Multicenter Randomized Controlled Study
NCT04720924CI-TRIAL-00077519completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of our study was to assess the performance of esophagogastroduodenoscopy automatic quality-control system in real-time quality control of EGD.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophagogastroduodenoscopy | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Computer-aided Real-time Automatic Quality-control System | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- AQCS-aided group
- description
- Patients in AQCS-aided group will go through white light EGD examination with assistance of AQCS.
- interventionNames
- Device: Computer-aided Real-time Automatic Quality-control System
- type
- NO_INTERVENTION
- label
- Control group
- description
- Patients in control group will go through white light EGD examination without AQCS.
Primary outcomes (1)
- measure
- Detection rate of early cancer and precancerous lesions on upper gastrointestinal tract confirmed by pathological examination
- timeFrame
- 6 months
- description
- The primary outcome is the detection rate of early cancer and precancerous lesions on upper gastrointestinal tract confirmed by pathological examination per group.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged 40-80 years old * Patients scheduled for white light EGD examination with anaesthesia * American Society of Anesthesiology risk class 1, 2 or 3 Exclusion Criteria: * Patients with known advanced esophageal or gastric cancer * Patients with a history of esophageal or gastric surgery * Patients scheduled for therapeutic EGD * Patients with stenosis or obstruction of upper gastrointestinal tract * Patients with a history of serious anesthesia-related complications * Patients in pregnancy or lactation phase * Patients refused to sign the informed consent
References
Publications (1)
- DERIVEDZhou R, Liu J, Zhang C, Zhao Y, Su J, Niu Q, Liu C, Guo Z, Cui Z, Zhong X, Zhao W, Li J, Zhang X, Wang H, Sun S, Ma R, Chen X, Xu X, Zhu Y, Li Z, Zuo X, Li Y. Efficacy of a real-time intelligent quality-control system for the detection of early upper gastrointestinal neoplasms: a multicentre, single-blinded, randomised controlled trial. EClinicalMedicine. 2024 Aug 30;75:102803. doi: 10.1016/j.eclinm.2024.102803. eCollection 2024 Sep. PMID 39281103