Clinical trial · Observational
Blood Sample Collection for Experimental Blood Test to Track Liver Cancer
Circulating MicroRNA Levels as a Predictor of Successful Bridging or Down-Staging Loco-Regional Therapy (LRT) to Liver Transplantation for Patients With Hepatocellular Carcinoma (HCC)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study investigates if an experimental blood test can help predict how well cancer will remain under control with treatment. Ther experimental blood test involves measuring mircoRNAs. MicroRNAs are small molecules which help regulate how genes are expressed. This information may help researchers guide treatment for other patients in the future.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (5)
- measure
- Patient Clinical Status - Liver Transplant
- timeFrame
- At study completion, up to 12 months
- description
- Undergoing liver transplant
- measure
- Patient Clinical Status - Death
- timeFrame
- At study completion, up to 12 months
- description
- Will assess the following: death
- measure
- Patient Clinical Status - Candidacy
- timeFrame
- At study completion, up to 12 months
- description
- No longer candidate for transplantation for reasons other than tumor progression
- measure
- Patient Clinical Status
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Provide signed and dated informed consent form * Willing to comply with all study procedures and be available for the duration of the study * Definite diagnosis of hepatocellular carcinoma established (by standard radiographic or histologic criteria) * Felt to be reasonable candidate for liver transplantation, potentially contingent on success of down-staging therapy Exclusion Criteria: * Either active or recent solid organ cancer other than hepatocellur carcinoma (HCC) within the last 5 years, unless determined by transplant hepatology team not to represent contra-indication to liver transplantation * Contra-indication to LRT (as assessed by interventional radiologist, for example severe thrombocytopenia, severe vascular disease precluding access, etc) * History of prior liver transplantation * Active or prior systemic therapy for HCC
References
Publications (0)
Data not yet available