Clinical trial · Interventional
Impact of a Sensory Rehabilitation Program on Olfactory-gustatory Alterations in Patients Treated With Chemotherapy for Haematological Cancer
NCT04716153CI-TRIAL-00101143RE-NEZ-SENSterminatedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Enrolement difficulties
Summary
Brief summary (as posted)
Proposition of a sensory rehabilitation program that could reduce the olfactory-gustatory alterations in patients who have been treated with chemotherapy for Haematological Cancer, and also improve their life quality, psychological well-being, and nutrition.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Haematological Cancer | — | UNRESOLVED | — |
| Lymphoma | Lymphoma | ONTOLOGY_EXACT | 0.90 |
| Multiple Myeloma | Multiple Myeloma | CURATED_EXACT | 0.92 |
| Olfactivo-gustatory Disorder | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Multifactorial sensory rehabilitation workshops | Other | — | UNRESOLVED |
| Tests and Questionnaire | Other | — | UNRESOLVED |
| Usual care | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Interventional
- description
- Patients in the interventional arm will follow a multifactorial sensory rehabilitation program focused on smell and taste that integrates several non-drug interventions, which are part of the current recommendations: program of workshops at the technical center, hydration of the mucous membranes with daily (3 times a day) liposomal sprays (LipoSaliva® and LipoNasal) between V0 and V1, presentation of visual dishes. The workshops will take place at the frequency of one session of 2 hours per week and will last for 3 weeks. Each session will accommodate a minimum of 2 participants. The program will include 3 workshops on olfactory rehabilitation and taste rehabilitation. Exercises (taking up the themes discussed) will be carried out at home between 2 workshops.
- interventionNames
- Other: Multifactorial sensory rehabilitation workshops
- Other: Tests and Questionnaire
- type
- OTHER
- label
- Control
- description
- The control group only receives the usual care provided for as part of routine care. It consists of a nutritional assessment at home by a dietician, with monitoring of intake and weight, in order to readjust nutritional support. A systematic search for oral mycosis is carried out in order to treat. The foods that the patient prefers, identified from a list of authorized foods, are preferred or even fortified. Patients in the control group will be able to benefit from the rehabilitation workshops if they wish at the end of the study.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Age between 18 and ≤ 75 years old * Patient with olfactory or gustatory disorders * Patient who has completed chemotherapy for haematological cancer Exclusion Criteria: * Eating disorder known prior to anti-cancer treatment, bulimic, anorexic or binge eating disorder (DSM-V criteria) * Refusal to sign the free and informed consent * Hypersensitivity to one of the components of liposomal sprays (Liposaliva® or liponasal®) * COVID + patient in the previous 3 months * Performance status ECOG 3 or 4 * Patient included in another clinical trial modifying taste / olfaction * Artificial nutrition post-chemotherapy * Known food allergies * Having a reading level in French that may interfere with a good understanding of the protocol and the questionnaires * Presenting visual or hearing deficits uncorrected to normal and which may affect the proper completion of the questionnaires * Patient under curatorship or tutorship. * Patient deprived of liberty * Pregnant or breastfeeding patient * Not be affiliated with a French social security scheme or beneficiary of such a scheme
References
Publications (0)
Data not yet available
No reference posted for this study.