Clinical trial · Interventional
Comparison of Erector Spina Plane Block and Thoracic Epidural Block
Comparison of Erector Spina Plane Block and Thoracic Epidural Block in Breast Surgery
NCT04702061CI-TRIAL-00051348completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this randomised controlled and double-blind study, is to compare the effects of erector spinae plane (ESP) and thoracic epidural (TEA) blocks on peri-operative hemodynamics and analgesia in patients undergoing unilateral mastectomies due to malignancy.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Neoplasms | Breast Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Pain, Postoperative | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Erector spina plane block before general anaesthesia | Other | — | UNRESOLVED |
| Thoracic epidural block before general anaesthesia | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Group E
- description
- Patients who receive general anesthesia after erector spina plane block
- interventionNames
- Other: Erector spina plane block before general anaesthesia
- type
- ACTIVE_COMPARATOR
- label
- Group T
- description
- Patients who receive general anesthesia after thoracic epidural block
- interventionNames
- Other: Thoracic epidural block before general anaesthesia
Primary outcomes (5)
- measure
- Sympathetic block level evaluation with skin conductivity
- timeFrame
- 45 minutes after block administration
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * ASA(American Society of Anesthesiologist) physical classification I-III * Patients undergoing unilateral mastectomies due to malignancy Exclusion Criteria: * Active infection at the intervention site * History of coagulopathy or anticoagulant use (less time has passed before peripheral and central blocks) * Major cardiac, pulmonary, renal and neurological diseases * Autonomic neuropathy or use of drugs that affect autonomic function * Patients with type 1 diabetes or insulin dependent type 2 diabetes over 10 years * Allergic to local anesthetics; * Patients who are uncooperative or have psychiatric problems * Morbidly obese (body mass index \> 35 kg/m2)
References
Publications (1)
- DERIVEDKurada G, Erdogan Kayhan G, Sanal S, Onay M, Gulec MS. Comparison of sympathetic block and hemodynamic effects of erector spinae plane block and thoracic epidural analgesia in breast surgery: a randomised controlled trial. BMC Anesthesiol. 2026 Feb 14;26(1):184. doi: 10.1186/s12871-026-03694-2. PMID 41691173