Clinical trial · Interventional
A Comparison of Gabapentin and Ketamine in Acute and Chronic Pain After Inguinal Hernia Repair
A Comparison of Gabapentin and Ketamine in Acute and Chronic Pain After Inguinal Hernia Repair: a Prospective Randomized Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients were randomized into two groups: Group Gabapentine ( G group) received 600 mg of Gabapentin (two tablets) two hours prior to surgery and saline solution before induction of spinal anesthesia and group Ketamine ( K group) received two placebo tablets and an injection of ketamine at a dosage of 0.15 mg/Kg before induction of spinal anesthesia.. During the surgery, blood pressure and heart rate were monitored. Postoperative analgesia was provided by a PCA morphine. Acute postoperative pain was assessed by a visual analog scale. The incidence of postoperative neuropathic pain was detected by the DN4 questionnaire after one and three months of surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chronic Pain Following Surgical Procedure for Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Gabapentin versus Ketamine | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Gabapentin group
- description
- group which receives 600 mg of Gabapentin (two tablets) one hour prior to surgery
- interventionNames
- Other: Gabapentin versus Ketamine
- type
- EXPERIMENTAL
- label
- ketamine group
- description
- group which receives an injection of ketamine at a dosage of 0.15 mg/Kg before surgery incision
- interventionNames
- Other: Gabapentin versus Ketamine
Primary outcomes (1)
- measure
- postoperative neuropathic pain
- timeFrame
- three months of surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * ASA I and II * Inguinal Hernia Repair in non emergent conditions Exclusion Criteria: * Patients with significant cardiovascular central nervous system disease, renal or liver failure could not operate the PCA device
References
Publications (0)
Data not yet available