Clinical trial · Interventional
Outcomes of Side-to-end Versus End-to-end Colorectal Anastomosis in Non-emergent Sigmoid and Rectal Cancers: Randomized Controlled Clinical Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Introduction: Cancer rectum and sigmoid is increasing nowadays. Resection and anastomosis is done laparoscopic approach with various techniques of anastomosis. Aim of this study: to compare between open side to end colorectal anastomosis versus laparoscopic end to end colorectal anastomosis in Non-emergent colo- rectal Cancers in adults as regard anastomotic leak, intestinal function and quality of life. Patients and Methods: Randomized controlled trial was performed on patients with Non-emergent colo rectal cancers between September 2016 and September 2018.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastrointestinal Neoplasms | Digestive System Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| open end end to end stapler anastomosis | Procedure | — | UNRESOLVED |
| openSide to end colorectal anastomosis . | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- antegrade colorectal single stapler anastomosis
- description
- open Side to end antegrade colorectal anastomosis colo rectal cancers.
- interventionNames
- Procedure: openSide to end colorectal anastomosis .
- type
- EXPERIMENTAL
- label
- open end to end colorectal stapler anastomosis
- description
- open end to end colorectal single anastomosis in non-emergent colo rectal cancers.
- interventionNames
- Procedure: open end end to end stapler anastomosis
Primary outcomes (2)
- measure
- : the incidence of the anastomotic leak during hospital admission and during 30 days postoperative.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * 1\. colo rectum adenocarcinoma proved by biopsy and histo-pathological examination. 2\. Only resections performed with immediate anastomosis, not under cover of stoma. 3\. Expected R0 resection. 4. patients \>18 years ,both sex 6. No previous history of stool or flatus incontinence, and clinically normal function of anal sphincter. Exclusion Criteria: 1. Patients younger than 18 years , Pregnant female. 2. Inability to understand the informed consent or refuse to participate or psychiatric patients. 3. Patients with recurrent cancer, Irresectable tumour, widespread loco-regional, distant metastasis ,Combination operation and Complicated cancer e.g. obstructed or perforated. 4. Cases covered by proximal stoma. 5. Patients with lesion \<3 cm from anal verge or cancer involving anal sphincter 6. preoperative chemo radiotherapy 7. Previous left sided colorectal surgery or anorectal surgeries. \-
References
Publications (0)
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