Clinical trial · Observational
"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".
NCT04690972CI-TRIAL-00103186LivMODrecruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Development of preclinical translational models for chronic liver tumors and diseases study, such as spheroids cultured in autologous medium and murine xenograft models to test the efficacy of new therapeutic strategies.
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chronic Liver Disease and Cirrhosis | — | UNRESOLVED | — |
| Liver Cancer | Malignant Liver Neoplasm | CURATED_EXACT | 0.92 |
| Non-Alcoholic Fatty Liver Disease | — | UNRESOLVED | — |
| Non-Alcoholic Steatohepatitis | — | UNRESOLVED | — |
| Viral Hepatitis B | — | UNRESOLVED | — |
| Viral Hepatitis C | — | UNRESOLVED | — |
| Viral Hepatitis D | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood sample during diagnostic test | Diagnostic Test | — | UNRESOLVED |
| Blood sample during surgery | Procedure | — | UNRESOLVED |
| Taking an additional biopsy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Hepato-bilio-pancreatic surgery
- description
- Patients whom hepato-bilio-pancreatic surgery is indicated as part of the care
- interventionNames
- Procedure: Blood sample during surgery
- label
- biopsy of the hepatic parenchyma
- description
- Patients whom a biopsy of the hepatic parenchyma, one or more hepatic nodules or a loco-regional treatment is indicated as part of the care
- interventionNames
- Procedure: Taking an additional biopsy
- label
- Viral chronic infection
- description
- Patients with a viral chronic liver disease
- interventionNames
- Diagnostic Test: Blood sample during diagnostic test
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients * diagnosed with chronic liver disease (viral or not) * diagnosed with at least one liver nodule for which a biopsy is planned as part of the care * for hepatobiliary surgery planned as part of care * for locoregional treatment for HCC is indicated 2. Patients able to receive and understand information relating to the study and give their written informed consent 3. Patients affiliated to the French social security system Exclusion Criteria: 1. Minor patients 2. Patients under legal protection, 3. Patients subject to legal protection or unable to express their consent, 4. Patients in a situation of social fragility, 5. Pregnant or breastfeeding woman, 6. No signing of informed consent.
References
Publications (0)
Data not yet available
No reference posted for this study.