Clinical trial · Observational
Sonazoid-enhanced Ultrasound for the Detection of Colorectal Liver Metastases Less Than 2 cm
Evaluation of Contrast Sonazoid-enhanced Ultrasound for the Detection of Colorectal Liver Metastases Less Than 2 cm
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Preoperative chemotherapy is often used for patients with colorectal cancer liver metastasis (CLM). Many small CLMs (\<=2cm) may disappear after chemotherapy, while most of these are still alive. Ultrasonography (US) is a common imaging modality for the intraoperative detection tumor. Sonazoid is new echo-contrast agent, which is more stable and sensitive for detecting of small tumor. Investigators initially this prospective study to compare the detection performance before and after using sonazoid.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Liver Metastasis Colon Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| After sonazoid | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Before sonazoid
- description
- US detection liver metastases before sonazoid
- label
- After sonazoid
- description
- US detection liver metastases after sonazoid
- interventionNames
- Diagnostic Test: After sonazoid
Primary outcomes (1)
- measure
- sensitive of detection tumor
- timeFrame
- 6 months
- description
- Change of the sensitivity detection liver tumors when using sonazoid enhanced ultrasound
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * Pathology confirmed colorectal adenocarcinoma * One or more liver metastases less than 2 cm * Multidisciplinary team recommend to perform preoperative chemotherapy * Have baseline EOB-MR before chemotherapy Exclusion Criteria: * Could not fulfill the criteria of no evidence of disease (NED) after hepatic resection/ablation/radiotherapy * With other malignancies
References
Publications (0)
Data not yet available