Clinical trial · Observational
Improving Cancer Survival and Reducing Treatment Variations With Protocols for Emergency Care
Improving Cancer Survival and Reducing Treatment Variations With Protocols for Emergency Care (ICARE)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Significant challenges and gaps remain in navigating transitions between acute care and outpatient care for many cancer survivors. This study underscores 1) implementation of Emergency Department (ED) risk-stratified treatments protocols that standardize patient care and would allow for rapid re-assessment and access to specialist care with well-coordinated cancer care plans, and 2) the significant numbers of minority cancer survivors seeking episodic care in the ED that are at increased risk of not receiving recommended post cancer treatment surveillance.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (4)
- measure
- ED utilization rate
- timeFrame
- 6 months from study entry
- description
- Emergency department utilization over 6 month period
- measure
- Mortality
- timeFrame
- 30 days from study entry
- description
- Mortality due to deep vein thrombosis/pulmonary embolism, due to sepsis, and overall mortality
- measure
- Mortality
- timeFrame
- 90 days from study entry
- description
- Mortality due to deep vein thrombosis/pulmonary embolism, due to sepsis, and overall mortality
- measure
- Mortality
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Cancer survivor (has had cancer in their lifetime, and is currently disease-free) * Verbal fluency in English or Spanish * Age 18-75 years Exclusion Criteria: * Unable to verbalize comprehension of study or impaired decision making (e.g., dementia) * Plans to move from Chicago area within the next year
References
Publications (5)
- BACKGROUNDSingh GK, Jemal A. Socioeconomic and Racial/Ethnic Disparities in Cancer Mortality, Incidence, and Survival in the United States, 1950-2014: Over Six Decades of Changing Patterns and Widening Inequalities. J Environ Public Health. 2017;2017:2819372. doi: 10.1155/2017/2819372. Epub 2017 Mar 20. PMID 28408935
- BACKGROUNDMoore JX, Akinyemiju T, Bartolucci A, Wang HE, Waterbor J, Griffin R. A prospective study of cancer survivors and risk of sepsis within the REGARDS cohort. Cancer Epidemiol. 2018 Aug;55:30-38. doi: 10.1016/j.canep.2018.05.001. Epub 2018 May 25. PMID 29763753
- BACKGROUNDConnolly GC, Francis CW. Cancer-associated thrombosis. Hematology Am Soc Hematol Educ Program. 2013;2013:684-91. doi: 10.1182/asheducation-2013.1.684. PMID 24319253
- BACKGROUNDNaess IA, Christiansen SC, Romundstad P, Cannegieter SC, Rosendaal FR, Hammerstrom J. Incidence and mortality of venous thrombosis: a population-based study. J Thromb Haemost. 2007 Apr;5(4):692-9. doi: 10.1111/j.1538-7836.2007.02450.x. PMID 17367492
- DERIVEDPrendergast HM, Khosla S. Lessons learned about policymaking: Moving an emergency department-initiated screening protocol to systemwide input in the development and implementation process. Acad Emerg Med. 2023 Jun;30(6):683-686. doi: 10.1111/acem.14672. Epub 2023 Feb 24. No abstract available. PMID 36707976