Clinical trial · Interventional
Nurse AMIE for Echo Show: Randomized Control Trial
NCT04673019CI-TRIAL-00057503completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Nurse AMIE platform has been modified for use as an Amazon Alexa skill for use on the Echo Show device. The investigators will recruit women receiving treatment for metastatic breast cancer and randomize patients to receive standard treatment (control) or the Nurse AMIE for Echo Show program. Nurse AMIE is a supportive care program for women undergoing chemotherapy and helps manage symptoms. The investigators will test the feasibility of using the Nurse AMIE program as well as its effectiveness at managing symptoms.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Metastatic Breast Cancer | Malignant Breast Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Nurse AMIE (Addressing Metastatic Individuals Every day) | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Immediate Intervention
- description
- The immediate intervention group will receive the intervention at the time of consent (baseline) and will be enrolled in the intervention for a total of 6 months: * Months 1- 3 (Approximately Day 1-Day 90) * Participant will receive the Echo Show, a pedometer (to track their steps) and an exercise band (to complete the exercise interventions). * Use of Nurse AMIE while receiving intervention phone calls from a study facilitator. We are interested in learning whether the phone calls are necessary or if the Nurse AMIE platform can stand alone and see the same effect. * Months 4-6 (Approximately Day 91-180) o Participant will continue to use Nurse AMIE, but without phone calls from study facilitator
- interventionNames
- Behavioral: Nurse AMIE (Addressing Metastatic Individuals Every day)
- type
- OTHER
- label
- Delayed Intervention
- description
- The delayed intervention group will receive the intervention 3 months after consent (3 months of no intervention followed by with 3 months of intervention, for a total of 6 months); the participant will follow the pattern listed below: * Months 1- 3 Approximately (Day 1-Day 90) o No use of Nurse AMIE * Months 4-6 (Approximately Day 91-180) * Participant will receive the Echo Show, a pedometer (to track their steps) and an exercise band (to complete the exercise interventions). * Use of Nurse AMIE while receiving intervention phone calls from a study facilitator
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Female patient with metastatic breast cancer receiving care at PSCI 2. Age: ≥18years of age 3. Personal in-home Wi-Fi access 4. Personal device capable of receiving telephone calls for weekly study facilitator check-ins 5. Fluent in written and spoken English 6. Sufficient vision/hearing to use the Alexa Echo Show. Exclusion Criteria: 1. ECOG Performance Status score of \>2 2. Patients with significant medical or psychiatric conditions (beyond breast cancer, its treatment, and its symptoms) that in the opinion of the research team exclude the subject from participation. 3. Receiving any behavioral intervention. 4. Pregnant 5. Cognitive impairment 6. Life expectancy of less than 6 months as determined by the treating physician
References
Publications (2)
- DERIVEDSchmitz KH, Kanski B, Gordon B, Caru M, Vasakar M, Truica CI, Wang M, Doerksen S, Lorenzo A, Winkels R, Qiu L, Abdullah S. Technology-based supportive care for metastatic breast cancer patients. Support Care Cancer. 2023 Jun 20;31(7):401. doi: 10.1007/s00520-023-07884-3. PMID 37338627
- DERIVEDGordon BR, Qiu L, Doerksen SE, Kanski B, Lorenzo A, Truica CI, Vasekar M, Wang M, Winkels RM, Abdullah S, Schmitz KH. Addressing metastatic individuals everyday: Rationale and design of the nurse AMIE for Amazon Echo Show trial among metastatic breast cancer patients. Contemp Clin Trials Commun. 2023 Jan 16;32:101058. doi: 10.1016/j.conctc.2023.101058. eCollection 2023 Apr. PMID 36698743