Clinical trial · Interventional
Embedded Palliative Care in Managing Symptoms in Participants With Recurrent Stage III-IV Thoracic Malignancies and Their Caregivers
Embedded Palliative Care in the Management of Advanced Thoracic Malignancies
NCT04662645CI-TRIAL-00070829completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This trial studies how well embedded palliative care works in managing symptoms in participants with stage III-IV thoracic malignancies that has come back and their caregivers. Embedded palliative care may improve distress and anxiety in participants and caregivers.
Conditions
Conditions (12)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Caregiver | — | UNRESOLVED | — |
| Malignant Pleural Neoplasm | Malignant Pleural Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Metastatic Thymic Carcinoma | Thymus Carcinoma | CURATED_BROADER | 0.80 |
| Recurrent Lung Carcinoma | Lung Carcinoma | CURATED_BROADER | 0.78 |
| Recurrent Thymic Carcinoma | Thymus Carcinoma | CURATED_BROADER | 0.80 |
| Stage IIIA Lung Cancer AJCC v8 | Malignant Lung Neoplasm | CURATED_BROADER | 0.78 |
| Stage IIIB Lung Cancer AJCC v8 | Malignant Lung Neoplasm | CURATED_BROADER | 0.78 |
| Stage IIIC Lung Cancer AJCC v8 | Malignant Lung Neoplasm | CURATED_BROADER | 0.78 |
| Stage III Lung Cancer AJCC v8 | Malignant Lung Neoplasm |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Palliative Therapy | Other | — | UNRESOLVED |
| Questionnaire Administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Supportive care (embedded palliative care)
- description
- Participants and caregivers undergo embedded palliative care comprising symptom management (physical and psychological), advanced directives and goals of care discussion, caregiver support, and referral for adjunctive supportive services as needed at each clinic visit.
- interventionNames
- Other: Palliative Therapy
- Other: Questionnaire Administration
Primary outcomes (17)
- measure
- Acceptance from providers to assess utilization of palliative care services
- timeFrame
- Up to 12 months
- description
- Acceptance will be evaluated utilizing provider surveys (to capture provider opinions on palliative care utilization) as well as rate of enrollment. Preliminary data will be summarized and collected. Confidence intervals will also be calculated for feasibility rates.
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with advanced or metastatic cancer of the chest (lung, thymus, or pleura): stage III or IV, recurrent disease * Patients will receive therapy (chemotherapy, immunotherapy, targeted therapy or radiation therapy) at The Ohio State University * New patients (defined as patients who have received no therapy for metastatic disease or have started treatment for metastatic disease within the last 30 days) or established patients with advanced cancer receiving anti-cancer therapy, no limit on prior therapies * Patient and caregiver must be able to read and understand consent form * Patients must designate a willing caregiver to participate although caregiver consent is not required for patient participation Exclusion Criteria: * Patients who are already enrolled or have been previously enrolled in palliative care or hospice services as an outpatient. Inpatient palliative care consultation prior to enrollment is permitted * Patients who do not qualify for active anti-cancer therapy and opt to enroll in hospice services prior to study enrollment * Patients who are unable to read or understand consent form * Patients receiving primary systemic treatment outside of Ohio State. Outside radiation therapy is permitted
References
Publications (0)
Data not yet available
No reference posted for this study.