Clinical trial · Interventional
The Effect of Acupressure Chemotherapy-related Nausea Vomiting in Children
Effectiveness of Acupress in The Management of Chemotherapy-Developed Acute Nausea Vomiting Symptoms In Child Oncology Patients
NCT04651608CI-TRIAL-00050452completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is carried out to evaluate and compare the efficiency of acupressure practice applied with pressure or sea-band and their placebo on managing the acute nausea-vomiting symptoms developing due to chemotherapy in pediatric oncology patients.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Nausea With Vomiting Chemotherapy-Induced | — | UNRESOLVED | — |
| Pediatric Cancer | Childhood Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| manuel acupressure | Behavioral | — | UNRESOLVED |
| placebo manuel acupressure | Behavioral | — | UNRESOLVED |
| placebo sea-band | Behavioral | — | UNRESOLVED |
| sea-band acupressure | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- manuel acupressure
- description
- In this group, manual acupress was applied to children receiving chemotherapy with moderate and high emetogenic effects.
- interventionNames
- Behavioral: manuel acupressure
- Behavioral: placebo manuel acupressure
- type
- EXPERIMENTAL
- label
- sea-band acupressure
- description
- In this group, sea-band acupressure was applied to children receiving chemotherapy with moderate and high emetogenic effects.
- interventionNames
- Behavioral: sea-band acupressure
- Behavioral: placebo sea-band
Primary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 5 Years
- Maximum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Children between the ages of 5-18, * Who have a chemotherapy protocol with a high and moderate emetogenic effect according to MASCC / ESMO Antiemetic Guidance Classification * Not having a verbal communication disorder. Exclusion Criteria: * If the participants did not receive chemotherapy or were receiving it for the first time, * Branching, redness, phlebitis, edema, open wound, fracture, infection, etc. in the wrist * Any obstacles for the verbal assessment of the child (intubation, etc.).
References
Publications (3)
- BACKGROUNDDupuis LL, Kelly KM, Krischer JP, Langevin AM, Tamura RN, Xu P, Chen L, Kolb EA, Ullrich NJ, Sahler OJZ, Hendershot E, Stratton A, Sung L, McLean TW. Acupressure bands do not improve chemotherapy-induced nausea control in pediatric patients receiving highly emetogenic chemotherapy: A single-blinded, randomized controlled trial. Cancer. 2018 Mar 15;124(6):1188-1196. doi: 10.1002/cncr.31198. Epub 2017 Dec 19. PMID 29266260
- BACKGROUNDJones E, Isom S, Kemper KJ, McLean TW. Acupressure for chemotherapy-associated nausea and vomiting in children. J Soc Integr Oncol. 2008 Fall;6(4):141-5. PMID 19134445
- BACKGROUNDMiao J, Liu X, Wu C, Kong H, Xie W, Liu K. Effects of acupressure on chemotherapy-induced nausea and vomiting-a systematic review with meta-analyses and trial sequential analysis of randomized controlled trials. Int J Nurs Stud. 2017 May;70:27-37. doi: 10.1016/j.ijnurstu.2017.02.014. Epub 2017 Feb 14. PMID 28231440