Clinical trial · Interventional
Comparison of TOETVA and Conventional Thyroidectomy
Comparison of Transoral Endoscopic Thyroidectomy Vestibular Approach and Open Conventional Thyroidectomy for Inflammatory Responses, Pain and Patient Satisfaction: A Prospective Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Introduction-Objective: The application of transoral endoscopic thyroidectomy vestibular approach (TOETVA) is gradually increasing recently. However, it is not clear whether TOETVA is a true minimally invasive thyroidectomy compared to open conventional thyroidectomy. In this study, we aimed to evaluate the TOETVA and open conventional thyroidectomy techniques in terms of postoperative inflammatory response, pain and patient satisfaction. Material and Method: In this prospective study, 40 female patients between the ages of 18-65 were divided into 2 groups of 20 patients: TOETVA: 20 patients, open thyroidectomy: 20 patients. Operation time, inflammatory response with IL-6, white blood cell (WBC) and C-reactive protein (CRP), postoperative pain, postoperative complications and patient satisfaction were evaluated in both groups.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Surgery | — | UNRESOLVED | — |
| Thyroid | — | UNRESOLVED | — |
| Thyroid Nodule | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| thyroid | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Conventional Thyroidectomy
- description
- Conventional Thyroidectomy
- interventionNames
- Procedure: thyroid
- type
- ACTIVE_COMPARATOR
- label
- Transoral endoscopic thyroidectomy vestibular approach
- description
- Transoral endoscopic thyroidectomy vestibular approach
- interventionNames
- Procedure: thyroid
Primary outcomes (5)
- measure
- Evaluate the TOETVA and Open Conventional Thyroidectomy Techniques in Terms of Postoperative Inflammatory Response by CRP (C-reactive protein)
- timeFrame
- 4 days
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Must be aged 18 to 65 years * Benign thyroid disease, with FNAB results Bethesda 3,4 or below 1 cm + Bethesda V, VI * Thyroid volume less than 50 cm3 * Largest nodule diameter must be less than 4 cm * No previous neck, chin and oral surgery * No vocal cord paralysis for any reason * In the preoperative period, clinically euthyroid and laboratory results in the euthyroid state * Agreed to participate in the study were included in the study.. Exclusion Criteria: * Patients with a FNAB result of Bethesda V, VI over 1 cm, * Planning of central and/or lateral neck dissection due to thyroid cancer * Patients with thyroid volume greater than 50 cm3 * Secondary intervention cases * Patients with accompanying hyperparathyroidism * Patients with preoperative vocal cord paralysis (VCP) * Patients with ASA score III and IV * Patients who were started with TOETVA and converted to the conventional method intraoperatively
References
Publications (0)
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