Clinical trial · Observational
Improving Prenatal Parental Counseling in Cases of Sacrococcygeal Teratoma
Improving Prenatal Parental Counseling in Cases of Sacrococcygeal Teratoma: a Multicenter Retrospective Study With Review of the Literature
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Sacrococcygeal teratoma (SCT) is the most common fetal and neonatal tumor. However, predicting factors of evolution, sequelae and relapse are still unreliable because of small-cohort studies. This study aims at identifying prenatal and postnatal prognostic factors of evolution of SCT during pregnancy, of postnatal relapse, and of medium and long-term sequelae (urinary, digestive, esthetic, psychologic) in order to improve parental counseling when the diagnosis of SCT is made during pregnancy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Sacrococcygeal Teratoma | Sacrococcygeal Teratoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Sacrococcygeal teratoma
- description
- Fetuses and infants diagnosed with sacrococcygeal teratoma and cared for between 2007 and 2017 in the main Parisian fetal medicine and pediatric surgery units: Necker-Enfants Malades Hospital, Antoine Béclère Hospital, Armand Trousseau Hospital, Robert Debré Hospital and Le Kremlin-Bicêtre Hospital.
Primary outcomes (3)
- measure
- Presence of postnatal sequelae
- timeFrame
- Up to 10 years
- description
- Presence of digestive, urinary, cosmetic or psychologic postnatal sequelae
- measure
- Fetal or neonatal death
- timeFrame
- Before 28 days of life
- description
- Intrauterine fetal death, termination of pregnancy or neonatal death
- measure
- Occurrence of benign or malignant recurrence
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 10 Years
Show eligibility criteria text
Inclusion Criteria: * Fetuses and infants (\< 1 year) diagnosed with benign sacrococcygeal teratoma * Cared for between January 2007 and December 2017 in the participating centers Exclusion Criteria: * Currarino syndrome * Other benign sacrococcygeal teratoma discovered after 1 year old or malignant sacrococcygeal tumors
References
Publications (2)
- RESULTVinit N, Bonnard A, Irtan S, Fouquet V, Ville Y, Rosenblatt J, Jouannic JM, Benachi A, Khen-Dunlop N, Lapillonne A, Beaudoin S, Rousseau V, Salomon LJ, Sarnacki S. Perinatal Prognostic Factors of Recurrence or Functional Sequelae in Neonatal Sacrococcygeal Teratoma, and Implications for Prenatal Counselling: A Multicenter Retrospective Study. J Pediatr Surg. 2025 Dec;60(12):162687. doi: 10.1016/j.jpedsurg.2025.162687. Epub 2025 Sep 17. PMID 40972984
- RESULTVinit N, Benachi A, Rosenblatt J, Jouannic JM, Rousseau V, Bonnard A, Irtan S, Fouquet V, Ville Y, Khen-Dunlop N, Lapillonne A, Jais JP, Beaudoin S, Salomon LJ, Sarnacki S. Growth velocity of fetal sacrococcygeal teratoma as predictor of perinatal morbidity and mortality: multicenter study. Ultrasound Obstet Gynecol. 2024 Nov;64(5):651-660. doi: 10.1002/uog.29110. PMID 39482803