Clinical trial · Interventional
Yoga Therapy During Chemotherapy and Radiation Treatment for the Improvement of Physical and Emotional Well-Being in Patients With Stage IB2-IIIB Cervical Cancer
Yoga Therapy During Chemotherapy and Radiation Treatment for Local-Regional Cervical Cancer
NCT04622670CI-TRIAL-00118152active not recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This trial studies how well yoga therapy works during chemotherapy and radiation treatment in improving physical and emotional well-being in patients with stage IB2-IIIB cervical cancer. Yoga therapy may help to balance the mind and body through exercise, meditation (focusing thoughts), and control of breathing and emotions.
Conditions
Conditions (12)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Adenocarcinoma | Cervical Adenocarcinoma | CURATED_BROADER | 0.80 |
| Cervical Adenosquamous Carcinoma | Cervical Adenosquamous Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Cervical Squamous Cell Carcinoma, Not Otherwise Specified | Cervical Squamous Cell Carcinoma | CURATED_BROADER | 0.80 |
| Stage IB2 Cervical Cancer FIGO 2018 | — | UNRESOLVED | — |
| Stage IB3 Cervical Cancer FIGO 2018 | — | UNRESOLVED | — |
| Stage IIA1 Cervical Cancer FIGO 2018 | — | UNRESOLVED | — |
| Stage IIA2 Cervical Cancer FIGO 2018 | — | UNRESOLVED | — |
| Stage IIA Cervical Cancer FIGO 2018 | — | UNRESOLVED | — |
| Stage IIB Cervical Cancer FIGO 2018 | — | UNRESOLVED |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Media Intervention | Other | — | UNRESOLVED |
| Quality-of-Life Assessment | Other | — | UNRESOLVED |
| Questionnaire Administration | Other | — | UNRESOLVED |
| Survey Administration | Other | — | UNRESOLVED |
| Yoga | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Group I (yoga group)
- description
- Patients attend at least 2 yoga classes per week over 5-6 weeks lasting approximately 60 minutes each for up to 15 classes during the CRT. Patients also complete surveys pre-treatment, once a week, and post-treatment over and receive a yoga manual and DVD during and after CRT.
- interventionNames
- Other: Media Intervention
- Other: Quality-of-Life Assessment
- Other: Questionnaire Administration
- Other: Survey Administration
- Procedure: Yoga
- type
- ACTIVE_COMPARATOR
- label
- Group II (wait list control)
- description
- Patients refrain from participating in any new stress management activities and receive a DVD. Patients are also offered 4 group yoga classes after 3 months of CRT. Patients also complete surveys as in Group I.
- interventionNames
- Other: Media Intervention
- Other: Quality-of-Life Assessment
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Score of =\< 2 on Eastern Cooperative Oncology Group (ECOG) performance scale * Able to speak English * Federation of Gynecology and Obstetrics (FIGO) stage IB2 through IIIB biopsy-proven CxCa (adenocarcinoma, squamous cell carcinoma, and adenosquamous) with plan to undergo curative outpatient CRT at main campus MD Anderson Cancer Center Exclusion Criteria: * Medically documented restrictions at enrollment that could interfere with participation in the yoga interventions (i.e. uncontrolled vaginal bleeding) * Medical illness that would prevent administration of full-dose chemotherapy * Concurrent diagnosis of a second cancer * Prior hysterectomy * Neuroendocrine histology * Patients who are pregnant * It is standard procedure to administer a pregnancy test before the start of CRT. Patients are deemed not pregnant by virtue of urine pregnancy test (UPT) or testing of the blood. Due to radiation and the nature of the disease, a patient becoming pregnant while on study is highly unlikely. In the event a patient were to get pregnant, they would be removed from study because their radiation therapy (RT) might be stopped or fetus would be terminated, which might influence other parameters that are being measured * Patients with major psychiatric diagnoses (e.g., schizophrenia, bipolar disorder) * Patients with extreme mobility issues, and * Patients who have had a regular yoga practice (at least one time a month) in past 6 months prior to study enrollment or who are currently engaged in a regular mind-body practice
References
Publications (0)
Data not yet available
No reference posted for this study.